000 03011cam a2200325 a 4500
003 EG-GiCUC
008 160924s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.07.04.M.Sc.2016.Al.E
100 0 _aAlaa Ahmed Mohamed Mohee
245 1 0 _aEffect of ginkgo biloba leaf extract on sodium selenite induced cataract in rats /
_cAlaa Ahmed Mohamed Mohee ; Supervised Hassan Mohamed Salem , Abdelmonem Mohamed Nageib , Anhar Mohamed Gomaa Shehab
246 1 5 _aتأثير مستخلص أوراق الجنكو علي الجرذان المصابة بالكتاركت ( المياه البيضاء) المحث بسيلنيت الصوديوم
260 _aCairo :
_bAlaa Ahmed Mohamed Mohee ,
_c2016
300 _a157 Leaves :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Agriculture - Department of Agricultural Biochemistry
520 _aGinkgo biloba leaves were examined for their proximate analysis (based on dry wt). Flavonoid compounds in Ginkgo biloba leaves extract were estimated by using HPLC. Results of the proximate analysis revealed that moisture, ash, crude protein, total lipid, crude fiber and total carbohydrate of Ginkgo biloba leaves are 79.18%, 16.44%, 3.93%, 4.86%, 13.59%, and 74.77%, respectively. Isorhamnetin represents the highest amount (28.2056%) followed by catechin hydrate (15.1347%), eriodictyol (8.0492%), quercetin (5.5179%), ferulic acid(4.7164%), quercetrin (2.9307%), rutin (2.1532%), caffeine (2.0351%), narengin (1.5054%), apegenin (1.2922%), caffiec acid (0.9222%), hisperidin (0.8883%), luteolin (0.1544%), 7-hydroxy flavon(0.1186%) , kaempeferol (0.1135%), rosmarinic (0.1021%), narenginin (0.0892%), hispertin (0.0668%), beside other unknown flavonoid compounds. Cataract was induced in experimental animal by using sodium selenite. Animals were classified into eight groups, normal, cataract, normal and cataract groups treated with 40, 60,100 mg/kg bw G.B. Ophthalmic examination was done to all groups. The levels of Catalase, MDA, TAO, lipid profiles, liver and kidney functions were measured in serum and the levels of reduced glutathione, malondialdehyde and nitric oxide were estimated in the lens. The best results of lipid profile, oxidative stress markers, liver and kidney function were observed in the group treated with 100mg/kg b.w Ginkgo biloba extract. This study concluded that, a protective effect of Ginkgo biloba extract to delay or retard the progression of cataract development
530 _aIssued also as CD
653 4 _aFlavonoid compounds
653 4 _aGinkgo biloba leaves
653 4 _aproximate analysis
700 0 _aAbdelmonem Mohamed Nageib ,
_eSupervisor
700 0 _aAnhar Mohamed Gomaa ,
_eSupervisor
700 0 _aHassan Mohamed Salem ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c57838
_d57838