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008 161009s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.01.Ph.D.2016.Ha.I
100 0 _aHany Reda Mohamed Elgamal
245 1 0 _aIntraoperative magnesium sulphate versus nitroglycerine infusion effect on pulmonary hypertension in congenital cardiac defects /
_cHany Reda Mohamed Elgamal ; Supervised Azza Ezzat , Ikram Abdallah , Mai Madkour
246 1 5 _aدراسة مقارنه بين تأثير عقاري كبريتات الماغنسيوم و النيتروجلسرين على ضغط الشريان الرئوي المرتفع في مرضى عيوب القلب الخلقيه
260 _aCairo :
_bHany Reda Mohamed Elgamal ,
_c2016
300 _a115 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia
520 _aMgSO4 has been studied in PAH in neonates; however no relevant studies discussed its effect on PAH associated with congenital heart disease, as one of the challenges facing pediatric cardiac anesthesiologist due to its detrimental effect in arterial oxygenation and ventilator dependence. Methodology: We tested this hypothesis by infusing MgSO4 all through the corrective surgical procedure and measuring Pulmonary artery pressure, oxygenation index & alveolar arterial oxygen difference.Results: Magnesium sulphate infusion caused 10% reduction in mean PAP from 39±13 to 35 ± 9 mm.Hg. Oxygenation index improved being 2.9± 0.9 baseline, to become 2.7 ± 0.9 before CPB & 3.1 ± 1.4 after bypass which was statistically significant when compared to control group. Alveolar arterial oxygen difference readings were 271 ± 10.5 at baseline, 258 ± 15.3 before CPB, and 275 ± 17 after CPB & was statistically insignificant between both groups. There was statistically significant reduction in Heart rate before CPB but was not associated with hemodynamic instability.Conclusion: Magnesium sulphate is a drug that could produce a reduction in pulmonary artery pressure associated with improvement in oxygenation index & mild reduction in heart rate without occurrence of systemic hypotension
530 _aIssued also as CD
653 4 _aCongenital cardiac defects
653 4 _aMagnesium sulphate versus
653 4 _aNitroglycerine infusion
700 0 _aAzza Ezzat ,
_eSupervisor
700 0 _aIkram Abdallah ,
_eSupervisor
700 0 _aMai Madkour ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aEnas
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c57982
_d57982