| 000 | 02767cam a2200337 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031554.0 | ||
| 008 | 161011s2016 ua d f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.08.03.Ph.D.2016.Em.A | ||
| 100 | 0 | _aEman Galal Nouman | |
| 245 | 1 | 0 |
_aAnalysis of some imidazole ring containing drugs / _cEman Galal Nouman ; Supervised Hayam Mahmoud Lotfy , Maisa Yaquob Youssef , Medhat Ahmed Alghobashy |
| 246 | 1 | 5 | _a{uFE97}{uFEA3}{uFEE0}{uFBFE}ل {uئإ٩١}{uئإأأ}ض ا{uئإؤئ}{uئإإ٣}ر{uئإؤآ}{uئإ٩١}{uئإ٨إ}ت ا{uئإؤئ}{uئإإ٣}{uئإء٣}{uئإ٩٧}و{uئآئإ}{uئإإء} {uئإأآ}{uئإإ٠}{uئإئ٠} {uئإء٣}{uئإإ٠}{uئإؤ٨}{uئإإء} ا{uئإئ٩}{uئإإ٣}{uئآئإ}دازول |
| 260 |
_aCairo : _bEman Galal Nouman , _c2016 |
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| 300 |
_a190 , 45 P. : _bcharts ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry | ||
| 520 | _aThis thesis is concerned with the analysis of three selected drugs containing imidazole ring namely, dabigatran etexilate, fenticonazole nitrate, and butoconazole nitrate. In this work, different analytical techniques were applied for stability indicating determination of dabigatran etexilate, in its pharmaceutical preparations using spectrophotometric methods, densitometric and liquid chromatographic method. LC-MSMS method was developed for determination of dabigatran etexilate and its active metabolites, dabigatran and dabigatran o-glucuronide in human plasma. Stability of fenticonazole nitrate was studied and stability indicating HPLC method was developed and applied for simultaneous determination of fenticonazole nitrate, methyl and propyl parabens in their laboratory prepared mixtures and in their pharmaceutical preparation. Accelerated stability study and pre-formulation studies were carried out on fenticonazole in cream dosage form. Stability of butoconazole nitrate was studied and stability indicating UPLC method was developed and applied for simultaneous determination of butonazole nitrate, methyl and propyl parabens in their laboratory prepared mixtures and in their pharmaceutical preparation. LC-MSMS method was developed and validated for sensitive determination of butoconazole in human plasma | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aButoconazole | |
| 653 | 4 | _aDabigatran | |
| 653 | 4 | _aFenticonazole | |
| 700 | 0 |
_aHayam Mahmoud Lotfy , _eSupervisor |
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| 700 | 0 |
_aMedhat Ahmed Alghobashy , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aEnas _eCataloger |
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| 905 |
_aNazla _eRevisor |
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| 942 |
_2ddc _cTH |
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| 999 |
_c58013 _d58013 |
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