000			02994cam a2200325 a 4500
003			EG-GiCUC
008			161015s2016 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.24.Ph.D.2016.La.E
100	0		_aLameece Moustafa Mohamed
245	1	4	_aThe evaluation of fundus autofluorescence as a prognostic factor for post injection visual improvement in diabetic macular edema / _cLameece Moustafa Mohamed ; Supervised Sherif Mohamed Sheta , Randa Mahmoud Abdelrazek , Gihan Helmy Abdelhalim
246	1	5	_aتقييم توهج الذاتى لقاع العين للتكهن بمدى تحسن قوة الإبصار بعد الحقن فى حالات الأرتشاح السكرى للماقولة
260			_aCairo : _bLameece Moustafa Mohamed , _c2016
300			_a119 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Ophthalmology
520			_aMethods: forty eyes with non-ischemic cystoid or diffuse edema underwent SW-FAF imaging with a cSLO prior to and after three intravitreal injections of bevacizumab and pattern of hyperautofluorescence was determined (number and total area of hyperautofluorescent spots). SD OCT was done to determine the CFT, integrity of the IS/OS junction and detect other visually significant findings. The primary outcome was to determine the changes in FAF and the secondary outcome was determining whether there is an association between baseline and post injection visual acuity and FAF findings.Results: 35 cases (87.5%) had abnormal foveal hyperautofluorescence: four showed a single spot of hyperautofluorescence (11.4%) and 31 showed multiple spots (88.6%). Pre injection the mean BCVA was best for those with no then multiple then single spots and post injection, the BCVA was best for those with multiple spots then no spots then single spots, but the differences were non significant. The total area of hyperautofluorescent spots was significantly greater for single than multiple spots both pre and post injection. On subdivision of cases into groups according to the change in their BCVA, in 23 cases the visual acuity improved, 15 remained the same and 2 cases deteriorated. The improved viusal acuity group had lower CFT, less hyperautofluorescent spots and a slightly greater total area of hyperautofluorescence but the differences were not significant. Conclusion: there are certain FAF patterns in DME, but they cannot be definitively correlated with vision or prognosis following therapy
530			_aIssued also as CD
653		4	_aDiabetic macular edema
653		4	_aFundus autofluorescence
653		4	_aOCT
700	0		_aGihan Helmy Abdelhalim , _eSupervisor
700	0		_aRanda Mahmoud Abdelrazek , _eSupervisor
700	0		_aSherif Mohamed Sheta , _eSupervisor
905			_aEnas _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c58075 _d58075