000 02975cam a2200325 a 4500
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008 161017s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.15.M.Sc.2016.No.C
100 0 _aNoha Yousry Ahmed Ahmed
245 1 0 _aCarbetocin versus combination of oxytocin and ergometrine for the prevention of postpartum hemorrhage following cesarean section /
_cNoha Yousry Ahmed Ahmed ; Supervised Gamal Gamal Eldin youssef , Hala Abdelwahab Abdellatef , Youssra Sameh lasheen
246 1 5 _aمقارنة عقار الكاربيتوسين بعقاقير الأوكسيتوسين و الميثرجين لمنع نزيف ما بعد الولادة عقب الولادة القيصرية
260 _aCairo :
_bNoha Yousry Ahmed Ahmed ,
_c2016
300 _a119 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics
520 _aPatients And Method: fifty primigravida women with gestational age more than 37weeks without any risk factors for postpartum haemorrhage undergoing elective or urgent caesarean section under regional were randomly divided into two equal groups: Group A: included 25 patients, they received Oxytocin 10 IU IV +ergometrine0.2 mg. Group B: included 25 patients, they received carbetocin, 100 mcg IV. The reason for administering additional uterotonic drugs in the oxytocin group (according to the operating obstetrician) was significantly more likely to be for PPH treatment. Results: The present study showed that results of comparison between two groups as comparing pre- and 24 hours post-operative hemoglobin (HB) between both groups results showed statistical significance in favoring of carbetocin group(p value <0.05) Again regarding estimated blood loss results are statistically significant. concerning maternal adverse effects in the form of elevated blood pressure there was statistical significance in which there was 28% elevation in the non carbetocin group. Again concerning nausea and vomiting they were significantly obvious in the non carbetocin group. Conclusion: combined intravenous carbetocin is effective to prevent atonic post-partum haemorrhage following cesarean section. It is as potent as combination of I.V syntocinon and ergometrine. In contrast with combination of syntocinon and ergometrine, carbetocin alone is one drug with less maternal adverse effects like elevated blood pressure, nausea and vomiting
530 _aIssued also as CD
653 4 _aCarbetocin
653 4 _aCesarean section
653 4 _aPostpartum hemorrhage
700 0 _aGamal Gamal Eldin youssef ,
_eSupervisor
700 0 _aHala Abdelwahab Abdellatef ,
_eSupervisor
700 0 _aYoussra Sameh lasheen ,
_eSupervisor
905 _aEnas
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c58142
_d58142