000			03075cam a2200325 a 4500
003			EG-GiCUC
008			161023s2016 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.33.M.Sc.2016.Ya.R
100	0		_aYasmine Mohamed Gaber Murad
245	1	0	_aRole of acoustic radiation force impulse (ARFI) As noninvasive diagnostic tool in focal hepatic lesions / _cYasmine Mohamed Gaber Murad ; Supervised Mahasen Abdelrahman Mabrouk , Ayman Mohamed Rashad Amer , Dalia Abdelhamid Omran
246	1	5	_aدور جهاز قياس المرونة المعتمد على قوة اندفاع الاشعاع الصوتي كآداة تشخصية غير تداخلية فى البؤر الكبدية
260			_aCairo : _bYasmine Mohamed Gaber Murad , _c2016
300			_a97 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine
520			_aBackground: Diagnosis of focal hepatic lesions ( FHLs) by modern imaging expose the patients to risks of contrast medium-induced side effects and irradiation hazards. Acoustic Radiation Force Impulse (ARFI) represents a new imaging method able to non-invasively assess the elastic properties of target tissues.Aim Of The Work: This study was designed to assess the validity of ARFI elastography as a non-invasive method for characterization of FHLs especially hepatocellular carcinoma (HCC). Methods: We enrolled 170 participants in the study, 120 patients with FHLs {uFD3E}88 HCC, 13 hemangioma, 13 metastatic, 6 other lesions), 30 patients with liver cirrhosis and 20 person as normal control groups. Patients were subjected to: Demographic, clinical, laboratory tests, abdominal ultrasound, triphasic CT or MRI, liver biopsy in some patients, stiffness of FHLs and liver parenchyma were measured by ARFI. Results: Of 120 patients with FHLs (77.3 % of HCC group were males, with mean age 59.4± 8 years. Among non- HCC group, 50% were males with mean age 49.7±11 years), a Cut off value of 2.59 m/s of liver stiffness (LS) measured by ARFI can predict occurrence of HCC in cirrhotic patients, sensitivity 78.4% and specificity 72%. For liver tumors, the mean stiffness values were 2.2± 0.7m/s for HCC (n=76), 1.96± 0.7 m/s for hemangioma (n=12), and 2.87± 1.07 m/s for metastasis (n=8). Concluson: ARFI could non-invasively provide significant information regarding the tissue stiffness, useful for predicting HCC occurrence in cirrhotic patients and differentiating HCC from metastases and hemangioma from metastases
530			_aIssued also as CD
653		4	_aAcoustic radiation force impulse (ARFI)
653		4	_aFocal hepatic lesions (FHLs)
653		4	_aHepatocellular carcinoma (HCC)
700	0		_aAyman Mohamed Rashad Amer , _eSupervisor
700	0		_aDalia Abdelhamid Omran , _eSupervisor
700	0		_aMahasen Abdelrahman mabrouk , _eSupervisor
905			_aEnas _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c58244 _d58244