000 | 02633cam a2200325 a 4500 | ||
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003 | EG-GiCUC | ||
008 | 161023s2016 ua dh f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.11.18.Ph.D.2016.En.B | ||
100 | 0 | _aEnas Mostafa Mohamed Darwish | |
245 | 1 | 0 |
_aBiomarkers associated with increased risk of atherosclerosis in patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome / _cEnas Mostafa Mohamed Darwish ; Supervised Aysha I. Z. Badawi , Alaa Abdelhamid , Mona Wasef |
246 | 1 | 5 | _aالدلالات المعملية المصاحبه لوجود تصلب الشرايين لدي مرضي الذئبة الحمراء و متلازمة الفوسفوليبيد |
260 |
_aCairo : _bEnas Mostafa Mohamed Darwish , _c2016 |
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300 |
_a127 P. : _bcharts , facsimiles ; _c25cm |
||
502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine | ||
520 | _aSystemic Lupus Erythematosus (SLE) is a chronic; usually life- long, potentially fatal autoimmune disease in which the immune system attacks various organs in the body. It occurs predominantly in women during reproductive age. SLE is characterized by multisystem microvascular inflammation with the generation of autoantibodies. It is also characterized by unpredictable exacerbations and remissions with various clinical manifestations. Antiphospholipid syndrome (APS) is a prothrombotic, systemic associated thrombosis and pregnancy morbidity. APS can occur as an isolated, primary condition or be associated with a connective tissue disorder such as systemic lupus erythematosus (SLE). Accelerated atherosclerosis (ATH) is more common and occurs much earlier in women with systemic lupus erythematosus (SLE) and it causes significant morbidity and mortality. Traditional risk factors do not fully explain the increased risk of cardiovascular disease, strongly suggesting that autoimmunity contributes to accelerated atherosclerosis. The aim of the research is to study the correlation between soluble TWEAK, serum leptin and the development of subclinical atherosclerosis in SLE patients and those with antiphosholipid syndrome | ||
530 | _aIssued also as CD | ||
653 | 4 | _aAntiphospholipid Syndrome | |
653 | 4 | _aAtherosclerosis | |
653 | 4 | _aSystemic Lupus Erythematosus | |
700 | 0 |
_aAlaa Abdelhamid , _eSupervisor |
|
700 | 0 |
_aAysha Ibrahim Zakiy Eldin Badawi , _eSupervisor |
|
700 | 0 |
_aMona Wasef , _eSupervisor |
|
905 |
_aEnas _eCataloger |
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905 |
_aNazla _eRevisor |
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942 |
_2ddc _cTH |
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999 |
_c58248 _d58248 |