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003 EG-GiCUC
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008 161029s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.10.05.Ph.D.2016.Fa.E
100 0 _aFatma Amer Abdelrehim Salama
245 1 0 _aExperimental studies on pathological and immunological aspects on avian influenza virus in SPF chickens /
_cFatma Amer Abdelrehim Salama ; Supervised Adel M. Bakeer , Mamdouh M. H. Afify , Mona M. Aly
246 1 5 _aدراسات تجربييه على جوانب باثولوجيه ومناعيه لفيروس انفلونزا الطيور فى الدواجن الخاليه من المسببات المرضيه
260 _aCairo :
_bFatma Amer Abdelrehim Salama ,
_c2016
300 _a163 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Clinical Pathology
520 _aThe present study was done to evaluate the pathological, immunological and molecular changes in response to two different vaccine regimes of avian influenza. In this study, we divided 100 SPF chicks into four groups; the first one was not vaccinated not challenged (Negative control). The second group was not vaccinated and challenged (Positive control), the third one was vaccinated with inactivated vaccine at 10 day alone. Finally, the fourth group was vaccinated with recombinant fowl pox vaccine at day old chicks and boosted with inactivated vaccine at 10 days old. The protection achieved from different two vaccination regimes was measured using quantitative RRT-PCR, humeral immunity measured using HI test .Lymphocyte proliferation assay using cell mediated immunity evaluation. In addition, pathological alteration and the viral load and distribution in different organs were described.
530 _aIssued also as CD
653 4 _aAvian influenza
653 4 _aImmunological
653 4 _aPathological
700 0 _aAdel Mohammed Bakeer ,
_eSupervisor
700 0 _aMamdouh Mahmoud Hafez Afify ,
_eSupervisor
700 0 _aMona Mehrez Aly ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c58349
_d58349