000 02909cam a2200349 a 4500
003 EG-GiCUC
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008 161105s2016 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.10.05.Ph.D.2016.Ma.L
100 0 _aMarwa Mohamed Mahmoud
245 1 0 _aLiver and kidney pathology in cattle naturally infected with fasciola /
_cMarwa Mohamed Mahmoud ; Supervised Mahmoud Samy Ahmad , Iman Bakr Mohamed , Gehan Ahmad Hosny
246 1 5 _aالتغيرات المرضية بالكبد و الكلى فى الابقار المصابة طبيعيا بطفيل الفاشيولا
260 _aCairo :
_bMarwa Mohamed Mahmoud ,
_c2016
300 _a135 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Clinical Pathology
520 _aThe current study was carried out to study the most important pathological changes in liver and kidneys in animals infested by fascioliasis and to detect fasciola antigen in livers and kidneys specimens. The total 80 cases of liver affected by fascioliasis showed different lesions in livers. The most important pathological changes in livers varied from acute to chronic liver cirrhosis and the detected antigen by using immunoflurescent using (Sigma-F7887) whole molecule IgG antibbovine antibody-FITC produced in rabbit revealed antigen in liver capsules, liver cells, sections of mature and immature worm and in fibrotic portal tracts and hepatic artery. The immunoperoxidase gave positive results in the same regions In 65 case of. Kidneys specimens of same animals revealed the most important associated lesions which were proliferative glomerulonephritis, crescentic glomerulonephritis mesangiaproliferative glomerulonephritis, membranoproliferative glomerulonephritis, the renal blood vessels showed perivascular fibrosis, vaccuolation of the medial wall, thickening of some medial renal blood vesssls and hypertrophied by smooth muscle cells proliferation. The immunohistochemistry gave positive results in 50 cases of 65 case which exhibit lesions in kidneys (glomerular lesions, interstitial lesion, renal tubular changes and changes of renal blood vessels). The immunoflurescent using (Sigma-F7887) whole molecule IgG antibbovine antibody-FITC produced in rabbit gave positive results in renal tubules epithelial layers and in endothelial lining and adventitial layer of renal blood vessels
530 _aIssued also as CD
653 4 _aFasciola
653 4 _aKidneys
653 4 _aLiver
700 0 _aGehan Ahmad Hosny ,
_eSupervisor
700 0 _aIman Bakr Mohamed ,
_eSupervisor
700 0 _aMahmoud Samy Ahmad ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c58431
_d58431