000 02615cam a2200325 a 4500
003 EG-GiCUC
008 161106s2016 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.19.05.M.Sc.2016.Na.P
100 0 _aNancy Nabil Kamel Israel
245 1 0 _aPattern, management and impact of chest metastasis on survival outcome of osteosarcoma patients, NCI Egypt /
_cNancy Nabil Kamel Israel ; Supervised Mohamed Fawzy Ibrahim , Ahmad Mohammed Kamel , Asmaa Ibrahim Abdelaziz Salama
246 1 5 _aنمط و تأثير ثانويات الصدر على معدل حياة مرضى أورام العظام (الأوستيوساركوما) بالمعهد القومى للأورام بمصر
260 _aCairo :
_bNancy Nabil Kamel Israel ,
_c2016
300 _a163 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology
520 _aOsteosarcoma accounting for about 56 % of all bones cancers in individuals under the age of 20 years. Although the overall survival has improved dramatically, yet it remains a challenging disease especially in developing countries. Was to find the survival outcome in metastatic osteosarcoma and its correlation to different prognostic variables. Sixty one (61) of newly diagnosed OS patients who presented to national cancer institute, Cairo university, Egypt from January 2008 To December 2013 were considered eligible in this retrospective study, data of the included patients were collected, that included age, gender, primary tumor size, initial lung metastases, lung metastases features, and management approach of lung metastases. The 3 year PFS was found to be 3%. The 3 year OS was 20% with a median survival of 23 months. Analysis of data in our study revealed statistically significant positive correlation between PFS and resectability (p value < 0.007), and negative correlation found with time to local control (P value < 0.02), while other factors were insignificant. Positive correlation was found between OS and resectability of lung metastases (P value0.04), yet other factors showed no statistical significance
530 _aIssued also as CD
653 4 _aLung metastases
653 4 _aMetastasectomy
653 4 _aOsteosarcoma
700 0 _aAhmad Mohammed Kamel ,
_eSupervisor
700 0 _aAsmaa Ibrahim Abdelaziz Salama ,
_eSupervisor
700 0 _aMohamed Fawzy Ibrahim ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c58464
_d58464