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008 161128s2016 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.08.03.Ph.D.2016.Om.A
100 0 _aOmnia Ali Mahmoud Elnaem
245 1 0 _aAnalysis of different pharmaceutical combinations used in treatment of common cold /
_cOmnia Ali Mahmoud Elnaem ; Supervised Azza Aziz Mohamed Moustafa , Maha Abdelmonem Hegazy , Dalia Mohamed Mamdouh
246 1 5 _a {u200F} {u200F}تحليل التركيبات الدوائية المختلفة المستخدمة في علاج نزالت البرد
260 _aCairo :
_bOmnia Ali Mahmoud Elnaem ,
_c2016
300 _a417 P. :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520 _aThis thesis is divided into three parts. In part one, general introduction on selected drugs used in treatment of common cold, their structure, physical properties, chemistry and pharmacological effects of the studied compounds. A summary of the reported methods developed for their analysis were also stated. In part two, different analytical methods utilizing chromatographic, spectrophotometric and potentiometric techniques were developed and validated for simultaneous determination of a ternary mixture of chlorpheniramine maleate, pseudoephedrine HCl and ibuprofen in pure form, laboratory prepared mixtures and pharmaceutical formulation. In part three, different analytical methods utilizing chromatographic, spectrophotometric and potentiometric techniques were developed and validated for simultaneous determination of a ternary mixture of carbinoxamine maleate, pholcodine and ephedrine HCl in presence of sunset yellow (coloring matter) in pure form and in pharmaceutical dosage form. All the proposed methods were validated according to the ICH guidelines and were successfully applied to pharmaceutical dosage forms. All the obtained results were within accepted range
530 _aIssued also as CD
653 4 _aChlorpheniramine maleate
653 4 _aIbuprofen
653 4 _aPseudoephedrine HCl
700 0 _aAzza Aziz Mohamed Moustafa ,
_eSupervisor
700 0 _aDalia Mohamed Mamdouh ,
_eSupervisor
700 0 _aMaha Abdelmonem Hegazy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c58813
_d58813