| 000 | 03038cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031621.0 | ||
| 008 | 161204s2016 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.11.33.M.Sc.2016.Mo.R | ||
| 100 | 0 | _aMohamed Hosney Farouk Ali | |
| 245 | 1 | 0 |
_aRole of fibroscan in the management of patients with hepatocellular carcinoma / _cMohamed Hosney Farouk Ali ; Supervised Ashraf Omar Abdelaziz , Aisha Mahmoud Elsharkawy , Mohamed Ibrahim Saif Elnasr |
| 246 | 1 | 5 | _aدور جهاز الفيبروسكان في علاج مرضي أورام سرطان الكبد |
| 260 |
_aCairo : _bMohamed Hosney Farouk Ali , _c2016 |
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| 300 |
_a158 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine | ||
| 520 | _aBackground: Hepatocellular carcinoma (HCC) is a challenging malignancy of global importance it is associated with a high rate of mortality and its prevalence in the world is increasing. In the management of HCC, attention must be focused on the presence and degree of the underlying chronic liver disease at first observation, which will influence the choice of the treatment. Transient elastography (FibroScan®; Echosens SA, Paris, France) is a non-invasive method that uses measurements of liver stiffness (LS) to assess hepatic fibrosis in patients with chronic liver disease. Aim of work: evaluation of the role of fibroscan in deciding the treatment modality for patients with hepatocellular carcinoma. Results: - TACE was done in 74patients (72.5%) with median of liver stiffness (LS) 27.8Kpa.Patients who did MWA were 16 patients (15.7%) with median of LS 24 Kpa. Surgical resection was done to 5patients (4.7%) with median of LS 34.3Kpa and 7 patients (6.9%) received combined treatment with median of LS 34.8 Kpa. Significant relation between LS and both size of spleen (p-value=0.023) and severe portal hypertension (p-value=0.042). MELD score was the only independent factor that affect the choice of TACE [OR: 1.208 (95% CI: 0.998-1.462)]. MELD score and the size of the focal lesion were the only independent factors that affect the choice of microwave [OR: 0.750 (95% CI: 0.593-0.948) and 1.483 (95% CI: 1.015-2.167 respectively]. Concolusion : Liver stiffness by Fibroscan is important to assess liver condition in patients with HCC and to predict portal hypertension but may not help in deciding the treatment modality for HCC | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aHepatocellular carcinoma | |
| 653 | 4 | _aPortal hypertension | |
| 653 | 4 | _aTransient elastography | |
| 700 | 0 |
_aAisha Mahmoud Elsharkawy , _eSupervisor |
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| 700 | 0 |
_aAshraf Omar Abdelaziz , _eSupervisor |
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| 700 | 0 |
_aMohamed Ibrahim Saif Elnasr , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aSoheir _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c58879 _d58879 |
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