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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.07.M.Sc.2016.Em.R
100 0 _aEmad Sayed Ewis
245 1 0 _aRapid detection of carbapenemase producing enterobacteriaceae using chromID® CARBA agar /
_cEmad Sayed Ewis ; supervised Mona Abdelaziz Wassef , Walaa Aboulkasem Ismail Shahin , Doaa Mohammad Abdelatty Ghaith
246 1 5 _aالكشف السريع للبكتريا المعوية المنتجة للكربابينيميز باستخدام كروم آي دي كاربا آجار
260 _aCairo :
_bEmad Sayed Ewis ,
_c2016
300 _a167 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
520 _aWith the increase in the use of carbapenems, the number of resistant bacteria with different resistance mechanisms is rising. Some resistance mechanisms include deactivating antibiotics, altering or producing excessive amount of drug target receptors by protein gene mutation, acquiring a new gene that produces insusceptible target, reducing the permeability of cell membrane to antibiotics and also removing active drug from periplasm or from inside of cell. Among the most important resistance mechanisms against carbapenem is producing carbapenemase The increased worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) emphasizes the need for a sensitive screening procedure to identify these microorganisms.Gastrointestinal carriers may serve as the reservoir for cross-transmission in the health care setting, and thus active surveillance is a key part in preventing the spread of such strains.Method: in our study a new Chrom ID CARBA AGAR (Biomerieux) was used for rapid detection of CRE cases in different departments of Abo elreish hospital. Results and conclusion: It was found that the prevalence of CRE carriers is 70 % in different departments. The sensitivity of Chrom ID CARBA AGAR was 100 % and the Specificity was 80 %
530 _aIssued also as CD
653 4 _aChrom ID CARBA AGAR
653 4 _aCRE
653 4 _aRapid detection
700 0 _aDoaa Mohammad Abdelatty Ghaith ,
_eSupervisor
700 0 _aMona Abdelaziz Wassef ,
_eSupervisor
700 0 _aWalaa Aboulkasem Ismail Shahin ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aShaima
_eCataloger
942 _2ddc
_cTH
999 _c59194
_d59194