000			02983cam a2200349 a 4500
003			EG-GiCUC
005			20250223031646.0
008			170204s2016 ua o f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.24.05.M.Sc.2016.Ra.P
100	0		_aRania Alfi Ayad Karas
245	1	2	_aA photo and thermal stability study of synthesized ascorbic acid / hydroxyapatite nanocomposite and its effect on human dermal fibroblasts cell lines / _cRania Alfi Ayad Karas ; Supervised Mohamed Abdelharith Mohamed , Abeer Attia Tawfik , Mahmoud Ashour Abdelsamad Sliem
246	1	5	_aدراسة الثبات الطوئى و الحرارى لمركب نانوى من حمض الاسكوربيك و الهيدروكسى ابتيت و تأثيره على خطوط خل{u٠٦٥٤}ايا انسجة ليفية آدمية
260			_aCairo : _bRania Alfi Ayad Karas , _c2016
300			_a118 P. : _bphotographs ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - National Institute of Laser Enhanced Science - Department of Laser Applications in Environmental Photochemistry and Agriculture
520			_aThis thesis mainly sought to produce and characterize a new ascorbic acid (AA) compound has a high stability profile. In addition, it investigated the cytotoxic effects and the proliferation rate of the synthesized composite on adult human dermal fibroblasts cells. It also sheds light on the immense therapeutic potential of AA as a free radical scavenger. For decades, it has been a common practice throughout the world to use AA in cosmetic preparations and skin care blends. Ascorbic acid has been extensively utilized for maintaining healthy resilient skin and treating hyperpigmentation. AA is essential for rebuilding skin collagen as it promotes collagen biosynthesis and generally functions as an antioxidant mitigates and neutralizes the effects of free radicals which are generating ubiquitous within our bodies by overexposure to UV radiation, environmental pollutants and stress. It also decreases hyperpigmentation because it is affecting the levels of glutathione which inhibits melanin production; it converts the inactive oxidized glutathione back to its active form. Despite all these benefits of AA, we claim that most of them have not been optimally exploited yet because AA associated with many problems such as its poor stability in air, light, and at high temperatures and its rapid decomposition into inactive compounds
530			_aIssued also as CD
653		4	_aFibroblasts cell lines
653		4	_aSynthesized ascorbic acid
653		4	_aThermal stability
700	0		_aAbeer Attia Tawfik , _eSupervisor
700	0		_aMahmoud Ashour Abdelsamad Sliem , _eSupervisor
700	0		_aMohamed Abdelharith Mohamed , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c59673 _d59673