| 000 | 03322cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031651.0 | ||
| 008 | 170215s2016 ua do f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.09.08.M.Sc.2016.Lu.E | ||
| 100 | 0 | _aLubna Ehab Elshalakany | |
| 245 | 1 | 0 |
_aEvaluation of the effect of metronidazole loaded polylactic co glycolic acid nanoparticles polylactic co glycolic acid nanoparticles only on gingival bleeding index with open flap debridement in patients with chronic periodontitis : _bA split mouth randomized clinical trial / _cLubna Ehab Elshalakany ; Supervised Manal Hosny Mostafa , Maha Mohammad Sallam , Enji Ahmed |
| 246 | 1 | 5 |
_aلتقييم لاستخدام المترونيدازول المحمل على جزيئات النانو لحمض اللبنيك المتعدد مشارك مع حمض الجليكوليك المتعدد و جزيئات النانو لحمض اللبنيك المتعدد مشارك مع حمض الجليكوليك المتعدد فقط مع جراحة سديلية مفتوحة كمساعد فى علاج التهابات الانسجة حول السنية المزمنة : _bتقسيم الفم فى تجربه سريرية عشوائية |
| 260 |
_aCairo : _bLubna Ehab Elshalakany , _c2016 |
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| 300 |
_a119 P. : _bcharts , photographs ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology | ||
| 520 | _aThe primary goal of periodontal therapy is the alteration of subgingival biofilms present on periodontally diseased sites that could be associated with the progressive destruction of the supportive periodontal tissues. Studies evaluating the effect of locally delivered antimicrobials (LDAs) as an adjunctive therapy to periodontal surgery revealed evidence of improved clinical outcomes in terms of the greater PD reduction and/or clinical attachment gain compared to periodontal surgery alone. Therefore, the aim of the present to evaluate the effect of metronidazole-loaded PLGA nanoparticles combined with open flap debridement versus PLGA nanoparticles combined with open flap debridement on gingival inflammation in patients with chronic periodontitis. Split mouth design was applied where each patient presented 2 contalateral sites with PD {u2265} 5mm and these sites were randomly assigned to 1 of 2 groups as follows: Group I received OFD with local delivery of 2 ml of metronidazole loaded PLGA nanoparticles gel using a plastic syringe where 1 ml was delivered after debridement and the other 1 ml after suturing. Group II received OFD with local delivery of 2 ml PLGA nanoparticles gel using a plastic syringe where 1 ml was delivered after debridement and the other 1 ml after suturing | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aGingival bleeding index | |
| 653 | 4 | _aMetronidazole loaded polylactic co glycolic acid nanoparticles | |
| 653 | 4 | _aPatients with chronic periodontitis | |
| 700 | 0 |
_aEnji Ahmed , _eSupervisor |
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| 700 | 0 |
_aMaha Mohammad Sallam , _eSupervisor |
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| 700 | 0 |
_aManal Hosny Mostafa , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aSamia _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c59852 _d59852 |
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