000			02995cam a2200325 a 4500
003			EG-GiCUC
008			170227s2016 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.10.04.Ph.D.2016.Is.A
100	0		_aIsmaiel Mostafa Ahmad Ali
245	1	0	_aAssociation between polymorphism of some myogenic regulatory factors and growth traits in bovine / _cIsmaiel Mostafa Ahmad Ali ; Supervised Elsaid Thabet Awad , Samy Ahmad Abdelaziz , Mohamad Ali Ahmad Warda
246	1	5	_aالأرتباط و العلاقه بين تعدد الأشكال الجينيه لبعض جينات العوامل المنظمه للعضلات و النمو فى الماشيه
260			_aCairo : _bIsmaiel Mostafa Ahmad Ali , _c2016
300			_a118 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Biochemistry and Chemistry of Nutrition
520			_aThe MyoD family of myogenic regulatory factors (MRFs) include several genes such as Myogenin (MyoG) and Myogenic Factor 5 (MYF5) that have the potential to influence economically important traits in beef cattle. The objective of the present study were to estimate the allele and genotype frequencies of the (MyoG) and (MYF5) genes in cattle and buffalo in Egypt and to determine the effects of these polymorphisms on some growth traits in the studied breeds. Genomic DNA was extracted from whole blood of 200 animals including Friesian cattle and buffalo. PCR-SSCP technique was used to genotype (MyoG) and (MYF5). Three genotypes were determined for MyoG exon-1 locus (BB, AB and AC) and two genotypes for MyoG exon- 1and intron-1 locus (AA and AB). Significant positive association were found between MyoG exon-1 AB genotype in Friesian cattle with weight at 6 months (W6) and average daily gain (ADG). For MyoG exon-1and intron-1 locus, the AA genotype showed positive effect on (ADG) in Friesian cattle. For MYF5 gene, exon-2 was monomorphic while three genotypes were determined for MYF5 intron-1 locus (BB, AB and AC) and four genotypes for intron-2 and exon-3 locus (AA, AB, AC and AD). Significant positive association was found between MYF5 intron-1 BB genotype in Egyptian buffalo with (W6) and (ADG). For intron-2 and exon-3 locus, the AD genotype in Friesian cattle and the AB genotype in Egyptian buffalo showed positive effect on (W6) and (ADG). These results could be included into marker assisted selection programs to improve the productivity in these breed
530			_aIssued also as CD
653		4	_aMyogenic factor 5
653		4	_aMyogenic regulatory factors
653		4	_aMyogenin
700	0		_aElsaid Thabet Awad , _eSupervisor
700	0		_aMohamad Ali Ahmad Warda , _eSupervisor
700	0		_aSamy Ahmad Abdelaziz , _eSupervisor
905			_aNazla _eRevisor
905			_aShaima _eCataloger
942			_2ddc _cTH
999			_c60017 _d60017