000 | 02052cam a2200325 a 4500 | ||
---|---|---|---|
003 | EG-GiCUC | ||
008 | 170315s2016 ua d f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aM.Sc | ||
099 | _aCai01.11.27.M.Sc.2016.Ri.C | ||
100 | 0 | _aRiham Farouk Gabr | |
245 | 1 | 0 |
_aChromogenic in situ hybridization (CISH) evaluation of human epidermal growth factor receptor 2 (HER 2) gene amplification in invasive duct carcinoma on tissue microarray TMA / _cRiham Farouk Gabr ; Supervised Amira Mohamed Raafat , Samir Ahmed Shawky , Rasha Ahmed Khairy |
246 | 1 | 5 | _aتقييم اختبار التهجين الموضعى الملون فى البحث عن تضخيم جين الهير- تو فى حالات سرطان قنوات الثدى الغازى و ذلك باستخدام تقنية مصفوفة الأنسجة |
260 |
_aCairo : _bRiham Farouk Gabr , _c2016 |
||
300 |
_a105 P. : _bcharts ; _c25cm |
||
502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology | ||
520 | _aHuman epidermal growth factor receptor 2 (HER2) is an important predictive marker in invasive duct carcinoma (IDC), for selecting anti-HER2 therapy candidates. Forty six IDC cases were tested for HER2 amplification by chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) on a tissue microarray (TMA). A non cost manual method using pencil tips was used to construct two TMA blocks, where each case was represented by three cores. Comparing CISH and IHC results, it was found that there was 100% concordance between both tests in cases of IHC scores (+3,+1,0), and lesser concordance values in IHC equivocal +2 cases | ||
530 | _aIssued also as CD | ||
653 | 4 | _aCISH | |
653 | 4 | _aHER 2 | |
653 | 4 | _aIDC | |
700 | 0 |
_aAmira Mohamed Raafat , _eSupervisor |
|
700 | 0 |
_aRasha Ahmed Khairy , _eSupervisor |
|
700 | 0 |
_aSamir Ahmed Shawky , _eSupervisor |
|
905 |
_aNazla _eRevisor |
||
905 |
_aSamia _eCataloger |
||
942 |
_2ddc _cTH |
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999 |
_c60272 _d60272 |