000 02288cam a2200325 a 4500
003 EG-GiCUC
008 170322s2016 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.12.08.M.Sc.2016.Mo.D
100 0 _aMohammed Osman Elhassan Hajelameen
245 1 0 _aDetermination of ramipril drug using new potentiometric sensors /
_cMohammed Osman Elhassan Hajelameen ; Supervised Gehad G. Mohamed , Eman Yossri Zaki , Marwa Elbadry Mohamed
246 1 5 _aتقدير عقار راميبريل بإستخدام محسات جهدية جديدة
260 _aCairo :
_bMohammed Osman Elhassan Hajelameen ,
_c2016
300 _a187 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Analytical Chemistry
520 _aIn this work, comparative study between MSPE and MCPE electrodes modified with different ion pairs and the ISPE and ICPE electrodes modified with different ion pairing agents was described. The electrodes were performed for the determination of ramipril in pure solution, pharmaceutical preparation and biological samples. The two types of electrodes were characterized and investigated with respect to the experimental parameters affecting their performance including temperature, pH, response time and interference. The electrodes showed good selectivity to RAM with respect to the interfering ions. Determination of ramipril in pharmaceutical form was performed using calibration and standard addition methods. Validation parameters such as accuracy, precision, linearity, specificity, limit of detection and limit of quantification were achieved. The sensors were applied successfully to determine RAM in pure form, pharmaceutical preparation and biological fluid samples. The developed method was found to be simple, accurate and precise when compared with the reported method
530 _aIssued also as CD
653 4 _aMCPE
653 4 _aMSPE
653 4 _aRamipril
700 0 _aEman Yossri Zaki ,
_eSupervisor
700 0 _aGehad G. Mohamed ,
_eSupervisor
700 0 _aMarwa Elbadry Mohamed ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c60361
_d60361