000			02429cam a2200325 a 4500
003			EG-GiCUC
008			170322s2016 ua f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.12.10.M.Sc.2016.Mu.S
100	0		_aMuhammed Ali Ramadan Ali
245	1	0	_aSynthesis of new heterocycles utilizing enamines precursors / _cMuhammed Ali Ramadan Ali ; Supervised Said Ahmed Soliman Ghozlan , Ismail Abdelshafy Abdelhamid , Amr Mohamed Abdelmoniem
246	1	5	_aتشييد حلقيات غير متجانسة الحلقة جديدة باستخذام الاينامينات كمواد بادئه
260			_aCairo : _bMuhammed Ali Ramadan Ali , _c2016
300			_a109 P. ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
520			_aThe original work of this thesis is composed of three parts. In the first part, a facile and convenient synthesis of an interesting N-(1H-pyrazol-5-yl)-hexahydroquinoline-3- carbonitrile and pyrazolo [4',3':5,6] pyrimido [1,2-a] quinoline-6-carbonitrile derivatives via the versatile readily accessible cyclic enaminones incorporating pyrazole moiety was accomplished. In the second part, the utility of cyclic enaminones with incorporated pyrazole moieties in the synthesis of different tetrahydro-1'H-spiro [indoline-3,4'- quinoline]-3'- carbonitrile and spiro [indoline-3,7'- pyrazolo [4',3':5,6] pyrimido [1,2-a]quinoline] derivatives. In the third part, the three component reaction of bis-isatins, malononitrile and dimedone or 1.3-dimethylbarbituric acid was investigated in ethanol at reflux in the presence of piperidine and afforded bis(spiro [chromene-4,3'-indoline]-3- carbonitrile) and bis(spiro[indoline-3,5'- pyrano [2,3-d] pyrimidine]-6'-carbonitrile) derivatives, respectively, in excellent yields. The chemical structures of all new synthesized products were confirmed based on the different spectral tools and elemental analysis data
530			_aIssued also as CD
653		4	_aHexahydroquinoline
653		4	_aMichael addition
653		4	_aÝ- enaminone
700	0		_aAmr Mohamed Abdelmoniem , _eSupervisor
700	0		_aIsmail Abdelshafy Abdelhamid , _eSupervisor
700	0		_aSaid Ahmed Soliman Ghozlan , _eSupervisor
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c60363 _d60363