000 03109cam a2200349 a 4500
003 EG-GiCUC
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008 170408s2015 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.19.04.M.Sc.2015.Jo.O
100 0 _aJohn Wahib Naguib Youssef
245 1 0 _aOutcome of surgery following neoadjuvant chemoradiotherapy for esophageal and gastroesophageal carcinomas :
_bA retrospective clinical study /
_cJohn Wahib Naguib Youssef ; Supervised Omaia Abdelhamid Nassar , Salem Eid Salem , Hebat Allah Gamal Eldin
246 1 5 _aدراسة اكلينيكية بأثر رجعى :
_bنتائج الجراحة ما بعد العلاج الكيميائى و الاشعاعى قبل الجراحة لسرطان المرئ و الوصلة الفؤادية
260 _aCairo :
_bJohn Wahib Naguib Youssef ,
_c2015
300 _a164 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology( Surgical)
520 _aBackground: Esophageal cancer is the eighth most common cancer and sixth most common cause of death from cancer worldwide. It is estimated that 16,980 people will be diagnosed with and 14,710 men and women will die of cancer of the esophagus. Neoadjuvant chemoradiotherapy has recently become the focus of interest in an effort to prolong survival and reduce recurrence rates in patients with esophageal cancer. Objective: The objective of this study is to determine National cancer institute experience about the role of preoperative chemoradiotherapy followed by esophagectomy for esophageal and gastro-esophageal carcinomas and its pathological outcome, resectability and the survival rate. Patients and methods: This retrospective study was conducted at the surgical oncology department of the National Cancer Institute, Cairo University. The study will include patients with oesophageal and oesophago- gastric carcinoma treated and followed up in NCI through the period from January 2010 to January 2015. Result : The age of the patients at the date of diagnosis ranged between 30 and 67 years. The most common histological type was squamous cell carcinoma (58%) while adenocarcinoma was 40% . The number who reached complete pathological response was 30%. The overall survival mean and median are best in patient receive neoadjuvant treatment by 12 months and 9.5 months respectively compared to 9 months and 4 months in group 2 . >2 years overall survival represented 10% of patients which was in stage 0 and IIA. As well as DFS was similar to OAS
530 _aIssued also as CD
653 4 _aEsophageal cancer
653 4 _aNeoadjuvant chemoradiotherapy
653 4 _aOesophago-gastric carcinoma
700 0 _aHebat Allah Gamal Eldin ,
_eSupervisor
700 0 _aOmaia Abdel hamid Nassar ,
_eSupervisor
700 0 _aSalem Eid Salem ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShaima
_eCataloger
942 _2ddc
_cTH
999 _c60559
_d60559