000 02738cam a2200325 a 4500
003 EG-GiCUC
008 170411s2016 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.04.Ph.D.2016.Sh.D
100 0 _aSherif Rizk Youssef
245 1 0 _aDifferentiating coronary artery aneurysms due to atherosclerosis or Kawasaki disease /
_cSherif Rizk Youssef ; Supervised Galal Elsaid , John Gordon , Hala Hamza
246 1 5 _aالتفرقة بين تمددات الشرايين التاجية المتحوصلة الناتجة عن تصلب الشرايين أو مرض كاوازاكي
260 _aCairo :
_bSherif Rizk Youssef ,
_c2016
300 _a153 P. :
_bfacsimiles ;
_c30cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology
520 _aBackground: The observed incidence of coronary artery aneurysms (CAAs) varies from 1.5%-4.9%. The two main causes for coronary aneurysms are atherosclerosis and Kawasaki disease (KD). Differentiation between both conditions is important because the prevention, management and prognosis is different. Antecedent KD is frequently missed in developing countries and misdiagnosed as measles, scarlet fever or acute rheumatic fever. Angiographic findings that make antecedent KD the likely cause for the coronary aneurysms from atherosclerosis include proximal location of the aneurysms with or without calcification, associated with angiographically normal distal segments. However, differentiating CAA due to KD versus atherosclerosis can be challenging. So can additional data obtained from IVUS and FFR help to differentiate between both types of aneurysms? Objectives: To test the hypothesis that clinical, demogrphic characteristics, IVUS and FFR can differentiate between KD and atherosclerotic CAAs after being classified according to their angiographic appearance. Methods: To investigate and study CAAs, angiograms and IVUS of 50 patients aged 8 to 60 years of age presenting with symptoms of myocardial ischemia at Cairo University Hospitals and Sharp Memorial Hospital from San Diego were blindly reviewed. Data collected included demographic characteristics, medical history, traditional cardiovascular risk factors, electrocardiographic, angiographic, IVUS and FFR findings
530 _aIssued also as CD
653 4 _aAneurysms
653 4 _aAtherosclerosis
653 4 _aKawasaki Disease
700 0 _aGalal Elsaid ,
_eSupervisor
700 0 _aHala Hamza ,
_eSupervisor
700 0 _aJohn Gordon ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aShaima
_eCataloger
942 _2ddc
_cTH
999 _c60639
_d60639