000			02854cam a2200325 a 4500
003			EG-GiCUC
008			170418s2016 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.04.Ph.D.2016.Am.C
100	0		_aAmir Anwar Shaker Samaan
245	1	0	_aChanges in ventricular structure and function after balloon mitral valvuloplasty : _bMagnetic resonance image follow-up study / _cAmir Anwar Shaker Samaan ; Supervised Wafaa Elaroussy , Karim Said , Magdi Habib Yacoub
246	1	5	_aتغيرات بنية و وظيفة البطين بعد توسيع الصمام الميترالى عن طريق البالون : _bدراسة متابعة باستخدام الرنين المغناطيسى للقلب
260			_aCairo : _bAmir Anwar Shaker Samaan , _c2016
300			_a166 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology
520			_aPrior studies have showed abnormal left ventricular (LV) function in patients with rheumatic mitral stenosis (MS). The pattern of LV remodeling after balloon mitral valvuloplasty (BMV) has not been well elucidated. To describe changes in global and regional LV myocardial function in patients with rheumatic MS using CMR 6 months and one year after successful BMV. Thirty patients (median age 33 years, 22 women) with isolated rheumatic MS were studied. All patients had CMR before, 6 months and one year after successful BMV. The following parameters were studied: indexed LV end diastolic and end systolic volumes (LVEDVI and LVESVI respectively), ejection fraction (EF), LV torsion, and regional and global LV deformation (analyzed at 17 LV segments using myocardial tissue tagging). Late gadolinium enhancement was studied to look for any myocardial fibrosis. At baseline, patients had median EF of 57 (range: 45-69) %, LVEDVI of 74 (44-111) ml/m2 and LVESVI of 31 (14-57) ml/m2 with absence of late gadolinium enhancement in all myocardial segments. Six months following BMV, compared to pre-BMV study, all LV myocardial segments showed significant improvement in strain parameters with significant increase in global longitudinal LV peak systolic strain (-16.4 vs. -13.8, p<0.001), global circumferential peak systolic strain (-17.8 vs. -15.6, p=0.002), base-apex LV torsion (3.3{u00B0} vs. 2.5{u00B0} p<0.001) and base -mid LV torsion 3.6 vs. 2.3{u00B0} p<0.001
530			_aIssued also as CD
653		4	_aBalloon
653		4	_aMitral valvuloplasty
653		4	_aVentricular structure
700	0		_aKarim Said , _eSupervisor
700	0		_aMagdi Habib Yacoub , _eSupervisor
700	0		_aWafaa Elaroussy , _eSupervisor
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c60670 _d60670