000 02992cam a2200349 a 4500
003 EG-GiCUC
005 20250223031717.0
008 170429s2016 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.28.Ph.D.2016.Ya.I
100 0 _aYasmin Saied Aly
245 1 0 _aInhaled versus intravenous magnesium sulphate in critically Ill infants and children with wheezy chest /
_bYasmin Saied Aly ; Supervised Hala Hamdy Shaaban , Hafez Mahmoud Bazaraa , Hanaa Ibrahim Rady
246 1 5 _aسلفات المغنيسيوم بالاستنشاق او عن طريق الوريد لعلاح الحالات الحرجة المصحوبة بضيق الشعب الهوائية فى الاطفال
260 _aCairo :
_bYasmin Saied Aly ,
_c2016
300 _a210 P. :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aWheezy chest remains one of the major causes for emergency department visits and admissions at pediatric intensive care units (PICUs). We aimed to determine the efficacy of magnesium sulfate (MgSo4) versus standard treatment in critically ill infants and children with wheezy chest. A randomized controlled trial comprised 81 patients suffering from wheezy chest divided into 3 groups. In addition to bronchodilators and systemic steroids, MgSo4 was given by inhalation in group A, intravenously in group B, and group C didn't receive MgSo4. The improvement in our cases was determined by clinical respiratory score (CRS), ventilator setting and arterial blood gases before and after treatment. Median age was 11 months, mean weight 9.3kg and the median of SOFA score was one. After treatment: There was significant improvement of CRS, respiratory rate and air entry in the three groups. Significant improvement in intercostals and subcostal retraction, mental state in group A and B; (p=0.03/0.002, p=0.0003/0.032; respectively). In group A, there was significant reduction in ventilator rate (p=0.017) and improvement of arterial/inspired oxygen ratio (p=0.0056). In group B, significant improvement in the color of the patients (p=0.0005) and a better mean arterial pH was noted (p=0.009). No significant rise in serum magnesium level. The median duration of oxygen supply and PICU stay was higher in group C compared to A and B. Magnesium sulfate is a safe and beneficial adjuvant therapy in addition to standard treatment in critically ill infants and children with wheezy chest
530 _aIssued also as CD
653 4 _aCritically ill infants and children
653 4 _aInhaled Mgso4
653 4 _aIV Mgso4
700 0 _aHafez Mahmoud Bazaraa ,
_eSupervisor
700 0 _aHala Hamdy Shaaban ,
_eSupervisor
700 0 _aHanaa Ibrahim Rady ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c60710
_d60710