000 | 02707cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223031723.0 | ||
008 | 170513s2016 ua h f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.08.07.Ph.D.2016.Ma.Q | ||
100 | 0 | _aMarwa Yehia Zakaria Elharirry | |
245 | 1 | 0 |
_aQuality control of some herbal preparations used in skin CARE / _cMarwa Yehia Zakaria Elharirry ; Supervsied Seham Salah Eldin Elhawary , Kamilia Fouly Taha , Hala Mohamed Elhefnawy |
246 | 1 | 5 | _aمراقبة الجودة لبعض المنتجات العشبية المستعملة فى العناية بالبشرة |
260 |
_aCairo : _bMarwa Yehia Zakaria Elharirry , _c2016 |
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300 |
_a237 P. : _bfacsimiles ; _c25cm |
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502 | _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy | ||
520 | _aDeveloping a herbal antifungal formulation containing eruca and garlic oils against highly resistant dermatophytes (Malassezia fufur AUMC No. 5173, Microsporum canis bodin AUMC No. 5490 and Trichophyton mentagrophytes AUMC No. 5501. 5501) and assessment of garlic oil thiosulfinates during the ex vivo percutaneous permeation through albino rat skin. Assay of antifungal activity was performed by filter paper disc method and agar well diffusion method. The components of volatile constituents and fixed oil of eruca seeds were studied using GC/MS. Thiosulfinates in garlic oil were analyzed by HPLC/UV. Both oils were incorporated into hair cream using span 60 and brij 58 at three different concentrations (2, 4 and 6% w/w) and alliin was ex vivo evaluated using albino rat skin mounted on Franz diffusion cells. The two oils have a synergistic effect on the first and additive effect on the second and the third fungi. The main constituents in eruca are 4-(methyl thio) butyl isothiocyanate (82%) for volatile constituents and erucic acid (40%) for the fixed one. The highest flux for alliin (0.337 ± 0.0015 mg/cm2/hr) was obtained at 4% surfactant concentration. Combination of oils has a high activity on the selected dermatophytes. Formulation of a herbal hair cream using span 60 and Brij 58 with a concentration 4% gives the highest permeation rate for alliin in garlic oil | ||
530 | _aIssued also as CD | ||
653 | 4 | _aDermatophytes | |
653 | 4 | _aEruca | |
653 | 4 | _aGarlic | |
700 | 0 |
_aHala Mohamed Elhefnawy , _eSupervisor |
|
700 | 0 |
_aKamilia Fouly Taha , _eSupervisor |
|
700 | 0 |
_aSeham Salah Eldin Elhawary , _eSupervisor |
|
856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aNazla _eRevisor |
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905 |
_aSamia _eCataloger |
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942 |
_2ddc _cTH |
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999 |
_c60880 _d60880 |