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003 EG-GiCUC
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008 170516s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.16.03.Ph.D.2016.En.I
100 0 _aEngy Samih Sadek Ali
245 1 0 _aInfluence of magnesium as a major contributor of water hardness on some cardiac disease risk factors in Egypt and south Africa /
_cEngy Samih Sadek Ali ; Supervised Hassan Mohamed Sobhy , Wafai Zaki Azer , Zeinab Khalil Elawamry
246 1 5 _aتأثير الماغنيسيوم كمساهم رئيسى فى عسر المياه على بعض المخاطر المؤدية لامراض القلب فى مصر و جنوب افريقيا
260 _aCairo :
_bEngy Samih Sadek Ali ,
_c2016
300 _a131 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Institute of African research and Studies - Department of Natural Resources
520 _aIn most African countries cardiovascular disease is now the second commonest cause of death after infectious disease, accounting for 10 % of total deaths and various ecological studies report a reduction in cardiovascular disease mortality risk with increasing magnesium levels in drinking water. Most of the studies done in this field were epidemiologic studies. The aim of this study was to examine whether magnesium addition to drinking water can affect risks of cardiac disease. The study included five groups of male albino rats. The rats received either tap water or water containing 5, 10, 20 g of magnesium sulfate per liter. During the whole experiment, all the groups received hypercholesterolemic diet except for the normal control which received normal basal diet. At the end of the experiment, blood was drawn for the determination of plasma magnesium, plasma glucose, lipid profile, liver function and kidney function. After the collection of blood samples, the rats were decapitated and their heart, liver, kidneys and pancreas were removed, weighed and subjected to histopathological examination. In addition, the extent of obesity was determined using the body mass index. In all groups magnesium addition was associated with higher levels of plasma magnesium. The blood analysis showed a significant decrease in serum total cholesterol, triglycerides, LDL- cholesterol and VLDL- cholesterol, while there was a significant increase in HDL- cholesterol in groups received magnesium sulfate in drinking water, compared with hypercholesterolemic group received tap water. There was a significant reduction in blood glucose concentrations in all magnesium treated groups compared to the hypercholesterolemic one
530 _aIssued also as CD
653 4 _aCardiac disease
653 4 _aHypercholesterolemia
653 4 _aRisk factors
700 0 _aHassan Mohamed Sobhy ,
_eSupervisor
700 0 _aWafai Zaki Azer ,
_eSupervisor
700 0 _aZeinab Khalil Elawamry ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c60928
_d60928