| 000 | 02354cam a2200313 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 008 | 170620s2016 ua o f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.12.25.M.Sc.2016.Ol.M | ||
| 100 | 0 | _aOla Muhamed Mansour Fathy Abdalla | |
| 245 | 1 | 0 |
_aMolecular basis of influenza a virus sensitivity to commercial drugs : _bScreening for novel antiviral compounds / _cOla Muhamed Mansour Fathy Abdalla ; Supervised Hamdi Mahmoud Hassaneen , Mohammed Ahmed Ahmed Ali |
| 246 | 1 | 5 |
_aالأسس الجزيئية لحساسية فيروسات الأنفلونزا إيه للعقاقير المتداولة : _bالبحث عن مضادات فيروسات جديدة |
| 260 |
_aCairo : _bOla Muhamed Mansour Fathy Abdalla , _c2016 |
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| 300 |
_a119 P. : _bphotographs ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology | ||
| 520 | _aIn Egypt, highly pathogenic avian influenza subtype H5NI virus (HPAIV/H5NI) was first reported in poultry in mid-february 2006 and declared to be endemic in 2008. The inadequate control measures enabled H5NI viruses to spread. Genetic drift in the virus was observed continuously each year and became more intense after 2008. Therefore, there is a necessity to develop new antiviral drugs targeting and eliminating the role of essential viral and cellular elements in the life cycle of the virus. The availability of drugs of different mode of actions would improve drug combination therapies to avoid the rapid emergence of drug-resistant viral strains. Despite, the re-emergence of amantadine-resistant HPAI H5NI and available reports about limited oseltamivir-resistant HPAI H5NI in Egypt which are based on theoretical sequence analysis of drug resistance markers, experimental studies to confirm the theoretical susceptibility of HPAI H5NI viruses to amantadine and oseltamivir are currently rare in Egypt | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aInfluenza a virus sensitivity | |
| 653 | 4 | _aMolecular basis | |
| 653 | 4 | _aNovel antiviral compounds | |
| 700 | 0 |
_aHamdi Mahmoud Hassaneen , _eSupervisor |
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| 700 | 0 |
_aMohammed Ahmed Ahmed Ali , _eSupervisor |
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| 905 |
_aNazla _eRevisor |
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| 905 |
_aSamia _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c61353 _d61353 |
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