000			02096cam a2200313 a 4500
003			EG-GiCUC
008			170716s2016 ua f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.12.10.M.Sc.2016.Ne.S
100	0		_aNesma Abdellattif Abdelfattah
245	1	0	_aSynthesis of novel bis (heterocycles) of expected useful applications / _cNesma Abdellattif Abdelfattah ; Supervsied Ahmed Helmy Elwhay , Ahmed Fathy Darweesh
246	1	5	_aتشييد حلقات غير متجانسة ثنائية متماثلة جديدة و متوقع لها تطبيقات مفيدة
260			_aCairo : _bNesma Abdellattif Abdelfattah , _c2016
300			_a169 P. ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
520			_aPart 1: A novel series of bis-tetrahydro [1,2,4] triazolo [5,1-b] quinazolin-8 (4H)-ones were prepared via the three component reaction of bis-aldehydes with 3-amino-1,2,4-triazole and dimedone. The reaction mechanism was studied. Unambiguous structural elucidation of the regioisomers was done using DFT calculations as well as 2D-HMBC spectroscopy. Part 2: The synthetic utility of 2-thioxo-1,2-dihydropyridine-3-carbonitriles 3, 4 and 4-oxo-6-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (19) as building blocks for novel bis-and poly(pyridines) as well as bis- and poly(pyrimidines) via alkylation with the corresponding bis-and poy(halo) compounds was investigated. Spectroscopic and theoretical studies confirmed the S-alkylation rather than the N-alkylation. The structures of all compounds are confirmed based on different spectral tools
530			_aIssued also as CD
653		4	_aBis-aldehydes
653		4	_aBis-tetrahydro [1,2,4] triazolo [5,1-b] quinazolin-8 4H-one
653		4	_aMulti-component reaction
700	0		_aAhmed Fathy Darweesh , _eSupervisor
700	0		_aAhmed Helmy Elwhay , _eSupervisor
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c61579 _d61579