000 01540cam a2200313 a 4500
003 EG-GiCUC
005 20250223031750.0
008 170802s2014 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aPh.D
099 _aCai01.34.Ph.D.2014.Ra.M
100 0 _aRadwa Yehia Mekky
245 1 0 _aMir-194 is a hepatocyte gate keeper hindering HCV entry through targeting tetraspanin CD81 /
_cRadwa Yehia Mekky ; Supervised Ahmed Ihab Abdelaziz , Gamal Esmat Gameel
260 _aCairo :
_bRadwa Yehia Mekky ,
_c2014
300 _a130 Leaves :
_bfacsimiles ;
_c30cm
502 _aThesis (Ph.D.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Molecular Pharmacology
520 _aCD81, a member of the tetraspanin membrane protein family, has been identified as an essential receptor for HCV (hepatitis C virus). Herein, we aimed at expioring the role of mircroRNas on regulating CD81 receptor expression. Bioinformatic analysis was carried out to select potential mircroRNAs that binds to CD81 3'untranslated region. Screening was dons in liver biopsies taken from twenty eight HCV genotype-4 (G4) patients and ten healthy donors
653 4 _aCD81
653 4 _aHCV
653 4 _aMir-194
700 0 _aAhmed Ihab Abdelaziz ,
_eSupervisor
700 0 _aGamal Esmat Gameel ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c61776
_d61776