000			01641cam a2200313 a 4500
003			EG-GiCUC
005			20250223031751.0
008			170806s2014 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aGift
097			_aM.Sc
099			_aCai01.34.M.Sc.2014.Sa.D
100	0		_aSarah Sameh Fayez Mohamed Darwish
245	1	0	_aDesign and synthesis of novel quinaziline derivatives as potential dual EGFR/NF- кB inhibitors / _cSarah Sameh Fayez Mohamed Darwish ; Supervised Ashraf H. Abadi , Mostafa Hamed
260			_aCairo : _bSarah Sameh Fayez Mohamed Darwish , _c2014
300			_a88 Leaves : _bcharts , facsimiles ; _c30cm
502			_aThesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
520			_aThe epidermal growth factor receptor (EGFR) is a membrane bound tyrosine kinase involved in callular signaling transduction pathways that control vital functions such as proliferation, differetiation and apoptosis . the overexpression of EGFR was observed in several types of cancers such as the non-samall cell lung carcinoma (NSCLC) which is among the most common causes of cancer-related death.
653		4	_aPotential dual EGFR/NF- кB inhibitors
653		4	_aThe epidermal growth factor receptor (EGFR)
653		4	_aThe non-samall cell lung carcinoma (NSCLC)
700	0		_aAshraf H. Abadi , _esupervisor
700	0		_aMostafa Hamed , _esupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c61834 _d61834