| 000 | 01674cam a2200289 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 008 | 170815s2014 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aGift | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.34.M.Sc.2014.En.M | ||
| 100 | 0 | _aEngi Atef Mahmoud Hassaan | |
| 245 | 1 | 0 |
_aMining ZINC database to discover potential phosphodiesterase 9 inhibitors using structure-based drug design approach / _cEngi Atef Mahmoud Hassaan ; Supervised Ashraf H. Abadi |
| 246 | 1 | 5 | _aإستخدام قاعدة البيانات زينك لإستكشاف مركبات محتملة مهبطة للفسفودايستراز 9 من خلال التصميم المبني علي التركيب الجزيئي |
| 260 |
_aCairo : _bEngi Atef Mahmoud Hassaan , _c2014 |
||
| 300 |
_a67 Leaves : _bchart , facsimiles ; _c30cm |
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| 502 | _aThesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry | ||
| 520 | _aPhosphodiesterase enzymes are regulators of several cellular and non cellular funcation including cell cycle, metabolism, erectile dysfunction, and cognition. Their actions are mediated through controlling the concentrations of thrir substrates cAMP an cGMP. phosphodiesterase 9 is a cGMP spcsific phosphodiesterase highly exressed in maliganant tissues, tumors, CNS , and spongy tissues. | ||
| 653 | 4 | _aMining ZINC database | |
| 653 | 4 | _aPhosphodiesterase 9 inhibitors | |
| 653 | 4 | _aPhosphodiesterase enzymes | |
| 700 | 0 |
_aAshraf H.Abadi , _esupervisor |
|
| 905 |
_aNazla _eRevisor |
||
| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c61987 _d61987 |
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