000 02980cam a2200349 a 4500
003 EG-GiCUC
005 20250223031803.0
008 170910s2016 ua ho f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.12.04.M.Sc.2016.Sh.S
100 0 _aShaima Mosaad Shoair
245 1 0 _aStudy of comparative dosimetry using the intensity-modulated therapy versus conventional tangential irradiation for breast /
_cShaima Mosaad Shoair ; Supervised Ahmed Soltan Monem , Ehab Marouf Attalla , Hassan Shafeik AbouElenin
246 1 5 _aدراسة مقارنة لقياس الجرعات باستخدام الاشعاع متغير الشدة مقابل الاشعاع التقليدى التماسى لسرطان الثدى
260 _aCairo :
_bShaima Mosaad Shoair ,
_c2016
300 _a78 P. :
_bfacsimiles , photographs ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics
520 _aPurposes of the study: to compare the dosimetry for breast cancer treatment plans using different radiotherapy treatment planning techniques. Materials and methods: twenty breast cancer patients were treated using three different radiotherapy techniques, including: 1) conventional tangential wedge-based fields (TW) carried out by 3D conformal radiotherapy (3DCRT), 2) two tangential inverse planning intensity-modulated radiotherapy (T-IMRT), and 3) multi-field IMRT (M-IMRT) carried out with seven beams. The planning target volume (PTV) and organs at risk (OARs), including heart, contralateral breast, contralateral lung and ipsilateral lung were delineated. The same dose constraints was used for all three plans with a prescribed PTV dose of 50 Gy. The volumetric doses of PTV and OARs were compared and analyzed using a dose volume histogram (DVH). The conformation number and homogeneity index were compared as well. Results: IMRT techniques found improved homogeneity and conformity of the dose to the target when compared to the TW. The M-IMRT found to significantly reduce the volume of the ipsilateral lung that receives 20 Gy when compared to the tangential techniques. For patients treated for the left breast, the M-IMRT and then T-IMRT, respectively, significantly reduced the percentage volume of the heart that received 30 Gy when compared to the TW. Conclusion: IMRT techniques achieve better results for PTV parameters and generally less dose to the OAR, although it increases the volume of the normal tissue that received a low dose.
530 _aIssued also as CD
653 4 _aBreast cancer
653 4 _aIMRT
653 4 _aTW
700 0 _aAhmed Soltan Monem ,
_eSupervisor
700 0 _aEhab Marouf Attalla ,
_eSupervisor
700 0 _aHassan Shafeik AbouElenin ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c62232
_d62232