000 02984cam a2200337 a 4500
003 EG-GiCUC
005 20250223031803.0
008 170910s2017 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.31.M.Sc.2017.Re.A
100 0 _aReem Mohamed Hamed Elshall
245 1 0 _aAssociation of diabetes mellitus with coronary atherosclerotic plaque burden and morphology measured by multidetector computed coronary angiography /
_cReem Mohamed Hamed Elshall ; Supervised Noha Hossam Eldein Ibrahim Behaire , Hazem Hamed A. Elhafiz Soliman
246 1 5 _aقياس مدى ارتباط داء السكرى بالعبء الناتج عن اللويحة المتصلبة بالشرايين التاجية و شكلها باستخدام الاشعة المقطعية متعددة المقاطع للشرايين التاجية
260 _aCairo :
_bReem Mohamed Hamed Elshall ,
_c2017
300 _a103 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
520 _aBackground: Coronary artery disease (CAD) is a leading cause of morbidity and mortality in patients with diabetes mellitus (DM). Diabetics have more prevalent, extensive coronary atherosclerosis than non-diabetics, with an accelerated progression and higher prevalence of multi-vessel disease. Diabetics have also a higher prevalence of silent atherosclerotic lesions and asymptomatic ischemia, making the diagnosis of CAD easier to miss and allowing the disease to progress to an advanced stage before becoming clinically evident. Objectives: To identify the features of CAD in diabetic patients using coronary CT angiography (CCTA). Conclusion: Diabetes is an independent predictor of CAD and is also associated with more advanced CAD, evaluated by indexes of coronary atherosclerotic burden. The comprehensive information regarding the presence, severity and type of plaque noninvasively provided by CCTA, has made possible a detailed characterization of the coronary disease pattern of diabetic patients at an earlier stage of disease. Diabetics have a significantly higher prevalence of plaques in every anatomical subset (number of vessel and either proximal or distal localizations) and for the different plaque composition (higher prevalence of mixed plaque). Since mixed plaque is associated with worse long-term clinical outcomes, these findings support more aggressive preventive measures in this population
530 _aIssued also as CD
653 4 _aAtherosclerotic burden
653 4 _aCoronary atherosclerotic plaque (CAP)
653 4 _aDiabetes mellitus (DM)
700 0 _aHazem Hamed A. Elhafiz Soliman ,
_eSupervisor
700 0 _aNoha Hossam Eldein Ibrahim Behaire ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c62235
_d62235