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003 EG-GiCUC
005 20250223031817.0
008 171002s2017 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.10.18.M.Sc.2017.He.P
100 0 _aHeba Fouad Mohamed Zeid
245 1 4 _aThe possible role of cattle and buffaloes in transmitting mycobacterium tuberculosis to man /
_cHeba Fouad Mohamed Zeid ; Supervised Osman Mohamed Hamed , Khaled Abdelaziz Abdelmoein
246 1 5 _aالدور المحتمل للابقار والجاموس فى نقل ميكروب السل الادمى للانسان
260 _aCairo :
_bHeba Fouad Mohamed Zeid ,
_c2017
300 _a77 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Zoonoses
520 _aMycobacterium tuberculosis is a human pathogen, but recent studies recorded the presence of M. tuberculosis in domestic animals. This work was carried out to investigate the possible role of cattle and buffaloes in the epidemiology of M. tuberculosis. For this purpose, 68 tuberculous tissue samples were collected from cattle and buffaloes from different organs at different slaughterhouses in Minoufiya government, Egypt. In addition to 7 sputum samples from patients showing signs of tuberculosis as well as blood samples from 92 persons with close contact with animals were also collected. DNAs were extracted from animal tuberculous lesions and sputum samples from patient to be examined by MTBDRplus assay for detection of Mycobacterium tuberculosis complex (MTC) and identify strains that show resistance to isoniazid and rifampicin. Moreover, DNAs were also examined for the presence of M. tuberculosis by conventional PCR. On the other hand, serum samples from 92 persons in intimate contact with animals were examined by ELISA for the presence of IgG antibodies against M. tuberculosis. Of the examined animal samples MTC and M. tuberculosis were detected in 88% and 11% respectively, and 29.4% showing drug resistance. All sputum samples from examined patients were M. tuberculosis positive, of these 57% showed drug resistance. 5.4% of human serum samples were positive for IgG antibodies against TB. In conclusion, detection of Mycobacterium tuberculosis in animals (cattle and buffalo), especially the drug resistant type, is a serious problem to human and animal health and wealth
530 _aIssued also as CD
653 4 _aBuffaloes
653 4 _aCattle
653 4 _aTuberculosis
700 0 _aKhaled Abdelaziz Abdelmoein ,
_eSupervisor
700 0 _aOsman Mohamed Hamed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c62673
_d62673