000			03136cam a2200325 a 4500
003			EG-GiCUC
008			171008s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.07.04.Ph.D.2017.Ra.P
100	0		_aRasha Salah Mohamed Ali
245	1	0	_aPreparation and evaluation of functional foods containing prebiotics and saccharomyces boulardii for combating diabetes complications in rats / _cRasha Salah Mohamed Ali ; Supervised Emam Abdelmobdy Abdelrahim , Mohamed Magdy Rashed , Madiha Mohamed Abdelkader
246	1	5	_aللحد من مضاعفات مرض السكرى فى الفئران Saccharomyces boulardii تحضير و تقييم أغذية وظيفية محتوية على بربيوتك و
260			_aCairo : _bRasha Salah Mohamed Ali , _c2017
300			_a169 P. : _bcharts , photographs ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Agriculture - Department of Agricultural Biochemistry
520			_aThe current study was planned to evaluate the hypoglycemic, hypolipidemic and antioxidant activities of some plants rich in prebiotic (chicory leaves, jerusalem artichoke, artichoke, psyllium seeds, barley, oat, fenugreek and locust bean) and two prepared type of symbiotic cheeses (first type was inoculated with saccharomyces boulardii and supplemented with 3% barley in powder form and the second type was inoculated with Lactobacillus gasseri and supplemented with 3% jerusalem artichoke in powder form) as a functional foods in rats fed high fat-high cholesterol diet then injected with low dose of streptozotocin to induce diabetes. In the first experiment of the present study the hypoglycemic, hypolipidemic and antioxidant activities of the aforesaid items were evacuated in diabetic rats fed on basal diet containing the aforesaid items each separately. Blood glucose, lipid profile, kidneys and liver functions as well as internal antioxidant enzymes activities were assayed. Also the histopathological changes of heart, liver, pancreas and kidney tissues of different experimental groups were examined. In the second experiment of the present study the hypoglycemic, hypolipidemic and antioxidant activities of chicory leaves, psyllium seeds, oat and fenugreek were evaluated in diabetic rats fed on high fat diet containing 20% of each plant separately. Results of the first experiment disclosed that all the studied items caused reduction in blood glucose, total cholesterol, LDL-C and triglycerides in addition to the improvement in kidneys and liver functions and the internal antioxidant enzymes activities. All the studied items retard the histopathological changes of heart, liver, pancreas and kidney tissues
530			_aIssued also as CD
653		4	_aDiabetes
653		4	_aPrebiotic
653		4	_aProbiotic
700	0		_aEmam Abdelmobdy Abdelrahim , _eSupervisor
700	0		_aMadiha Mohamed Abdelkader , _eSupervisor
700	0		_aMohamed Magdy Rashed , _eSupervisor
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c62812 _d62812