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003 EG-GiCUC
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008 171009s2016 ua do f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.12.04.Ph.D.2016.Ra.P
100 0 _aRania Mohammed Moussa
245 1 0 _aProbable complications from radiotherapy treatment of some tumour sites /
_cRania Mohammed Moussa ; Supervised Nader A. Elsherbini , Wafaa M. Khalil
246 1 5 _aاحتمالات المضاعفات الناتجه من العلاج الاشعاعى لبعض الاورام
260 _aCairo :
_bRania Mohammed Moussa ,
_c2016
300 _a154 P. :
_bcharts , photographs ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics
520 _aThe purpose of this study is to estimate tumor control probability (TCP) and normal tissue complication probability (NTCP) for estimating the expected clinical gain coming from 3DCRT (3dimension conformal radiotherapy) and IMRT (Intensity Modulated Radiotherapy) in the studied clinical sites which are prostate, breast and head and neck with the impact of the dose calculation algorithm, energy and number of treatment fields. XIO planning system version (4.51.00) has been used in this study supplied with two different calculation algorithms (superposition and convolution), and at 6 and 15 MV photon beam energy. For each clinical site, 12 IMRT plans are created and one conformal plan, IMRT plan were developed for 5, 7 and 9 fields, using both algorithms and both energies. The parameters of evaluation included dose volume parameters, TCP and NTCP. Results show that for prostate case, IMRT technique with 7 fields improve target conformity and provide better organ at risk (rectum and bladder) sparing in comparison with conformal as shown from the results of TCP and NTCP, and with insignificant difference according to energy and used algorithm. For breast case, IMRT technique with 5 fields improve target conformity and TCP in comparison with conformal technique with improvement in NTCP values
530 _aIssued also as CD
653 4 _aProbable complications
653 4 _aRadiotherapy treatment
653 4 _aTumour
700 0 _aNader A. Elsherbini ,
_eSupervisor
700 0 _aWafaa M. Khalil ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c62824
_d62824