000 02648cam a2200349 a 4500
003 EG-GiCUC
005 20250223031822.0
008 171009s2017 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.19.04.M.Sc.2017.Mo.N
100 0 _aMostafa Maher Elgammal
245 1 0 _aNeoadjuvant versus adjuvant chemotherapy in advanced ovarian carcinoma /
_cMostafa Maher Elgammal ; Supervised Hanan Ramadan Nassar , Ihab Samy Fayek , Alfred Elias Namour
246 1 5 _aمقارنة بين العلاج الكيمائى السابق أو اللاحق للجراحة فى سرطان المبيض المتقدم
260 _aCairo :
_bMostafa Maher Elgammal ,
_c2017
300 _a102 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology(Medical)
520 _aOvarian cancer is the fifth most common type of cancer and the most common cause of death among women with gynecological malignancies. The aim of this retrospective study was to assess whether there is an advantage of treating women with advanced ovarian cancer with chemotherapy before cytoreductive surgery (neoadjuvant chemotherapy (NACT)) compared with conventional treatment where chemotherapy follows maximal cytoreductive surgery. Methods and materials: Include patients with advanced epithelial ovarian cancer (stage III and IV) who underwent surgery from 2009-2015 with optimal cyto-reductive surgery (R0). Results: The study included 60 patients the mean age for all the patients was 53.7 years . A total of 60 patients diagnosed and treated in NCI and Agouza Police hospital in the specified period (2009-2015), with locally advanced epithelial ovarian carcinoma. They are divided into 2 groups according to pattern of treatment where 30 patients seemed resectable and primary cytoreductive surgery was carried out, and 30 patients seemed unresectable and neoadjuvant chemotherapy was given to them. On assessment of the survival we compared the whole number of both groups. The median overall survival time was 45.77 months in the conventional group and 49.06 month in the NACT group
530 _aIssued also as CD
653 4 _aAdvanced ovarian carcinoma
653 4 _aCompletecyto
653 4 _aNeoadjuvant chemotherapy
700 0 _aAlfred Elias Namour ,
_eSupervisor
700 0 _aHanan Ramadan Nassar ,
_eSupervisor
700 0 _aIhab Samy Fayek ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c62830
_d62830