000			03029cam a2200349 a 4500
003			EG-GiCUC
005			20250223031825.0
008			171015s2017 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.21.M.Sc.2017.Ky.R
100	0		_aKyrillos Maher Aziz Meshreky
245	1	0	_aRetinal microvessels and retinal optical coherence tomography findings in male patients with schizophrenia / _cKyrillos Maher Aziz Meshreky ; Supervised Aref Abdelhalim Khoweiled , Mohamed Abdelfattah Khalil , Dalia Hamed Khalil
246	1	5	_aالأوعية الدموية الدقيقة فى شبكية العين و نتائج الآشعة المقطعية الضوئية المتراصة فى المرضى الذكور المصابين بالفصام
260			_aCairo : _bKyrillos Maher Aziz Meshreky , _c2017
300			_a171 P. : _bcharts ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry
520			_aBackground: There is strong evidence that deficits in visual perception and early visual processing are associated with schizophrenia. These deficits include retinal venule widening, retinal nerve fiber layer (RNFL) thinning, dopaminergic abnormalities, abnormal output of retinal cells as measured by electroretinography (ERG). On the other hand, the retina is considered a window to the brain and it provides a good model for the study of neuronal pathology, since it lacks myelin. This means that any changes in the RNFL will reflect axonal damage. Aim of the study: To compare retinal microvessels in patients with schizophrenia to normal individuals using retinal fundus photography. To detect structural changes in the retinal layers of patients with schizophrenia in vivo using Spectral Domain-Optical Coherence Tomography (SD-OCT). Also, to relate retinal microvascular measures and OCT parameters to the severity of symptoms and clinical variables in schizophrenia. Methods: 30 patients with schizophrenia were recruited from Psychiatry and Addiction Hospital Kasr Al-Ainy inpatient wards and 30 healthy controls, matched in age, gender and educational level to the patients{u2019} group, were recruited from other departments of Kasr AL-Ainy hospitals. They were assessed regarding retinal fundus photography and OCT. In the patients group PANSS scale was used to assess the severity of symptoms. Results: Schizophrenic patients showed a statistically significant reduction in the average peripapillary RNFL thickness when compared to controls
530			_aIssued also as CD
653		4	_aOct
653		4	_aRetinal nerve fiber layer
653		4	_aSchizophrenia
700	0		_aAref Abdelhalim Khoweiled , _eSupervisor
700	0		_aDalia Hamed Khalil , _eSupervisor
700	0		_aMohamed Abdelfattah Khalil , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c62947 _d62947