000 02848cam a2200325 a 4500
003 EG-GiCUC
008 171017s2016 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.24.Ph.D.2016.Mo.C
100 0 _aMohamed Beshr Kenawy
245 1 0 _aClinico-pathological correlation of pre- descemet{u2019}s stromal layer (dua{u2019}s layer) in relation to corneal diseases and corneal surgery /
_cMohamed Beshr Kenawy ; Supervised Harminder Dua , Tarek Abdelmageed Katamish , Mohamed Hassaballa
246 1 5 _aالعلاقة الاكلينيكية - المرضية المتبادلة بين الطبقة اللحمية ما قبل غشاء ديسميت (طبقة دوا) و ارتباطها بأمراض و جراحة القرنية
260 _aCairo :
_bMohamed Beshr Kenawy ,
_c2016
300 _a122 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Ophthalmology
520 _aPurpose: To determine the role of a novel layer, pre-descemet{u2019}s layer (Dua{u2019}s layer) in posterior corneal pathology and corneal surgery. To study the characteristics of this new layer and to compare it with the rest of the stroma in terms of histology and biomechanical properties, namely scrolling and elasticity. To determine how does air travel through the cornea to create different types of bubbles. Design: Clinical and experimental lab based study. Methods: Clinical: A-cases with posterior corneal pathology were reviewed in highlight of the new layer. B-patients with endothelial dysfunction underwent endothelial keratoplasty with a new surgical technique. Experimental: The pre-descemet{u2019}s layer was isolated from eye bank eyes and its scrolling and elasticity were studied. Density of keratocytes in the posterior stroma and in the layer were analysed in fresh corneas. Air was injected in sclero-corneal discs and intrastromal passage of air was recorded. Results: There was clear evidence that the layer had a role in posterior corneal diseases such as hydrops and posterior corneal surgery. The layer had distinct histological and physical properties than the rest of the stroma. Conclusion: There exists a tough layer in the posterior stroma, with different properties than the rest of the stroma. This layer has clinical application to posterior stromal diseases, as well as an important role in posterior corneal surgery
530 _aIssued also as CD
653 4 _aDL
653 4 _aKeratocyte density
653 4 _aScrolling
700 0 _aHarminder Dua ,
_eSupervisor
700 0 _aMohamed Hassaballa ,
_eSupervisor
700 0 _aTarek Abdelmageed Katamish ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c62996
_d62996