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003 EG-GiCUC
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008 171017s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2017.Om.I
100 0 _aOmar Ahmad Hussein Mahmoud
245 1 0 _aInsulin requirements and glycemic control in young children with diabetes /
_cOmar Ahmad Hussein Mahmoud ; Supervised Mona Mamdouh Hassan , Noha Arafa Mohammad , Marise Antoun Fahmy
246 1 5 _aالاحتياجات من الانسولين و مستوى ضبط السكر بالدم عند الاطفال الذين لديهم مرض البول السكرى
260 _aCairo :
_bOmar Ahmad Hussein Mahmoud ,
_c2017
300 _a123 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground: Managing T1D in young children is challenging from medical and psychosocial perspectives. YC-T1D have high insulin sensitivity and nocturnal hypoglycemia is common. Young children have unique developmental challenges including normative dependence upon parental caretaking and labile self-regulation of behavior and emotions, eating , sleep and physical activity that may complicate T1D care. Objective: The aim of the study was to assess the characteristics of insulin therapy regarding type, dose and frequency, as well as degree of glycemic control achieved in young children with diabetes. Methods: Sixty-nine patients with type 1 DM, aged less than five years, following up at diabetes endocrine and metabolism unit (DEMPU), specialized pediatric hospital, Faculty of medicine, Cairo University in the period from March 2015 to June 2016 were recruited in the study. Results: the present study showed that diabetic ketoacidosis necessitating ICU management at diagnosis was present in 49 patients (71%), and hyperglycemia without ketosis in 20 patients (29%). 39/60 cases (65%) with mean HbA1c level {u2265}7.5%. more favourable control in terms of mean HbA1c level was noticed in those using NPH than those on Long acting analogue (8.0±1.3 vs 9.2±1.5, p=0.03) and in cases on regular short acting insulin than in cases on ultra short insulin (7.7±1.3 vs 8.5±1.3%,p=0.05). Ketoacidosis /hyperglycemia was responsible for (76.5%) of hospital readmissions; while hypoglycemia was a less frequent cause for readmission to hospital being reported in 20.6%
530 _aIssued also as CD
653 4 _aGlycemic control
653 4 _aInsulin requirements
653 4 _aYoung children
700 0 _aMarise Antoun Fahmy ,
_eSupervisor
700 0 _aMona Mamdouh Hassan ,
_eSupervisor
700 0 _aNoha Arafa Mohammad ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c62998
_d62998