000			02972cam a2200349 a 4500
003			EG-GiCUC
005			20250223031830.0
008			171023s2017 ua h f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2017.Ar.D
100	0		_aAreef Ramadan Ibrahim Atia
245	1	0	_aDyslipidaemia among Egyptian children : _bSingle center study / _cAreef Ramadan Ibrahim Atia ; Supervised Nehal Mohammed Elkoofy , Aya Mohammed Fattouh , Dina Hossam Eldine Hamed
246	1	5	_aاضطرابات شحوم الدم بين الأطفال المصريين : _bدراسة فى مركز واحد
260			_aCairo : _bAreef Ramadan Ibrahim Atia , _c2017
300			_a122 P. : _b facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aBackground: Dyslipidaemia is a major health problem among children which can lead to significant cardiovascular disease. Dyslipidemia could be primary which include familial hypercholestrolemia, familial hypertriglyceridemia and combined dyslipidemia or secondary to organ failure or drugs. Manifestations include xanthomas, xanthelasmata arcus cornae and rarely lipemia retinalis, but it may be asymptomatic. Complications include cardiovascular disease (diastolic dysfunction of both ventricles and atherosclerosis of the aortic root) and acute pancreatitis in case of hypertriglyceridemia. Treatment includes diet therapy, statins for hypercholestrolemia and fibrates for hypertriglyceridemia. Screening is very important to detect silent cases and prevent future complications. Methodology: Thirty children (15 males and 15 females) with dyslipidemia (25 cases with primary dyslipidemia and 5 cases with secondary dyslipidemia) were included. The cases were subjected to history taking and clinical assessment. Lipid profile was done for all cases and their relatives. Abdominal ultrasound and echocardiography were also done. Results: The median age of studied cases was 6.5 years, with a range of (1:16) years. Fifteen cases (50%) were males and 15 cases (50%) were females. Family history was present in 13 cases (43%). Seventy percent of cases had consanguineous parents. Thirty four percent of cases were accidently discovered while 40% were discovered during screening of the patients relatives. Xanthomas were present in 30%, xanthelasmata in 20% and arcus cornae in 33% of cases but no cases had lipemia retinalis. Fatty liver was detected in 40% of cases
530			_aIssued also as CD
653		4	_aChildren
653		4	_aDyslipidemia
653		4	_aEgyptian
700	0		_aAya Mohammed Fattouh , _eSupervisor
700	0		_aDina Hossam Eldine Hamed _eSupervisor
700	0		_aNehal Mohammed Elkoofy , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c63103 _d63103