000			02113cam a2200349 a 4500
003			EG-GiCUC
005			20250223031831.0
008			171024s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.08.09.M.Sc.2017.Do.M
100	0		_aDoaa Abdallah Zaky
245	1	0	_aModulation of intestinal gut barrier permeability by dipeptidyl peptidase IV inhibition in a model of rat septicemia / _cDoaa Abdallah Zaky B.Pharm ; Supervised Dalaal Moustafa Abdallah , Noha Nagah Nassar , Muhammad Yusuf Alshorbagy
246	1	5	_aتعديل نفاذية الحاجز المعوي بتثبيط ثنائي ببتيديل ببتيداز 4 في نموذج لتسمم الدم في الجرذان
260			_aCairo : _bDoaa Abdallah Zaky B.Pharm , _c2017
300			_a158 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy- Department of Pharmacology and Toxicology
520			_aBThe preferential role of the underlying PI3K/Akt (PKB) axis in triggering enterocytic proliferation/differentiation signaling and AJ assembly is still controversial. The involvement of CD26/DPP-IV in obstructive jaundice (OJ)-induced sepsis has not been yet reported VLD3/10/30 dose dependently modulated CD26/DPP-IV, GLP-1, IGF-1, PI3K, pS473-Akt, pS9-GSK-3Ý, pS133-CREB, and CD1. VLD3/10 increased E-cadherin and NPSH, however, they reduced pY654-Ý-catenin, portal and aortic endotoxin, NF-mB, TNF-Ü, MPO, TBARS, subepithelial/pericryptal and submucosal collagen deposition as well as vimentin immunoreactivity, effects that were quite opposed with VLD30.
530			_aIssued also as CD
653		4	_aAdherens junctions
653		4	_aOxidative stress
653		4	_aVildagliptin
700	0		_aDalaal Moustafa Abdallah , _eSupervisor
700	0		_aMuhammad Yusuf Alshorbagy , _eSupervisor
700	0		_aNoha Nagah Nassar , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c63119 _d63119