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003 EG-GiCUC
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008 171125s2016 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.12.05.M.Sc.2016.Ma.M
100 0 _aManar Magdy Abdelrahman
245 1 0 _aMolecular characterization of probiotics and its influence on autistic children /
_cManar Magdy Abdelrahman ; Supervised Youssef Imam A. Mawgoud , Nayra Shakar Mehanne
246 1 5 _aالتوصيف الجزيئي للبروبيوتيك و تأثيره على أطفال مرض التوحد
260 _aCairo :
_bManar Magdy Abdelrahman ,
_c2016
300 _a60 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Botany and Microbiology
520 _aChildren with autism always have gastrointestinal problems and symptoms, these problems are more severe than in healthy children. Probiotics are able to influence the composition of microbiota and the function of intestinal barrier and alter the immune responses of the mucosa. Bifidobacterium spp. and Lactobacillus spp. were assessed in stool samples of 40 autistic children and 20 healthy typical children of similar ages as control. The study indicated that the counts of both Bifidobacterium spp. and Lactobacillus spp. were lower in the stool of autistic children than that of their control group. It was significant in the case of Lactobacillus spp. with (P value 0.05) and highly significant in the case of Bifidobacterium spp. with (P value 0.000) and the count of bacteria wasn't affected by sex (male or female). After supplementation of the autistic children with a daily nutritional product consisting mainly of dried carrots fortified with probiotic strains (Bifidobacterium spp.) for 3 months, highly significant increase in the levels of both Bifidobacterium spp. and Lactobacillus spp. was observed in stool of the autistic children (P value 0.000 , 0.015) respectively. The results showed that the probiotic product led to improve autism scale in childhood (CARS) by 90%, in addition to improve deep sleep in 85% and communicate to speak 32%, and social networking 31.4%. Also, the food reduced children hyperactivity by 25%
530 _aIssued also as CD
653 4 _aAutism
653 4 _aBifidobacterium
653 4 _aProbiotic
700 0 _aNayra Shakar Mehanne ,
_eSupervisor
700 0 _aYoussef Imam A. Mawgoud ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c63669
_d63669