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003 EG-GiCUC
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008 171211s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.17.Ph.D.2017.He.E
100 0 _aHebatalla Saad Teleb
245 1 0 _aEffect of delta-aminolevulinic acid dehydratase polymorphism on susceptibility to lead poisoning among lead exposed workers /
_cHebatalla Saad Teleb ; Supervised Mona Sobhy Siha , Lalia Ahmed Rashed , Dalia Abdelhamid Shaker
246 1 5 _aتأثير تعدد الأشكال لحمض الدلتا أمينوليفولينك النازع للماء على القابلية للتسمم بالرصاص بين العمال المعرضين للرصاص
260 _aCairo :
_bHebatalla Saad Teleb ,
_c2017
300 _a173 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine- Department of Industrial Occupational and Environmental Medicine
520 _aIntroduction:Lead is used in ammunition industry. It has been associated with several health hazards among exposed workers. Aim:The aim of this work isto obtain some insights of the distribution of e-ALAD polymorphism among lead exposed workers and their effect on some hematological and renal indices. Subjective and methods:This study was conducted on 50 lead exposed workers compared to 50 non-exposed individuals, where full history, clinical examination, and laboratory investigations in the form of: genetic study of e-ALAD gene polymorphism, blood leadlevel, CBC, serum creatinine and urea, U-e-aminolevulinic acid, U-B2-microglobulin were done. Results:Statistically significant (p<0.05) differences were found between exposed and control as regards the prevalence ofhematological, renal, GIT and neurological manifestations. Compared to the control group, urinary B2-microglobulin, urinary e-ALADH, serum urea, serum creatinine and blood lead levelwere significantly higher among exposed workers, while significantlylowerin the mean values of complete blood picture (RBCs, Hb, MCV, MCH, MCHC and PLT)
530 _aIssued also as CD
653 4 _aAmmunition industry
653 4 _aBlood lead
653 4 _ae-ALAD Polymorphism
700 0 _aDalia Abdelhamid Shaker ,
_eSupervisor
700 0 _aLalia Ahmed Rashed ,
_eSupervisor
700 0 _aMona Sobhy Siha ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c63953
_d63953