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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.12.04.Ph.D.2017.Ha.E
100 0 _aHani Deosuki Masuad Awad
245 1 0 _aEffect of different types of prime solutions on pulmonary function after cardiopulmonary bypass /
_cHani Deosuki Masuad Awad ; Supervised Maha Anwar Ali , Hosam Salh Eldin Elashmawi
246 1 5 _aتأثير أنواع مختلفة من المحاليل الأبتدائية علي الوظائف الرئوية بعد التحويلة القلب الرئوية
260 _aCairo :
_bHani Deosuki Masuad Aawad ,
_c2017
300 _a102 P. :
_bcharts , photographs ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics
520 _aObjectives: Different types of colloidal priming for cardiopulmonary bypass (CPB) have been used to reduce fluid load and to avoid the fall of plasma colloid osmotic pressure (COP) that leads to edema formation and consequently can cause organ dysfunction. The discussion about the optimal priming composition, however, is still controversial. The present study investigated the effect of a hyperoncotic CPB-prime with hydroxyethyl starch (HES) 6% (200;0.5), 20% albumin in comparison to crystalloid (7.2% hypertonic saline (HS) and ringer) on pulmonary functions at post CPB is investigated. Methods: Participated in these study 125 patients randomly distributed in five groups according to CPB perfusate solution: Perfusate solution as follows: Ringer, HES, more concentrated HES, albumin and hypersaline prime were used for group1 to group5 sequentially. Hb conc., WBC count, albumin, serum creatinine, serum osmolarity, oxygen arterial tension and inspired fraction ratio (PaO2/FiO2), oxygen alveolar-arterial gradient (GA-aO2) and pulmonary shunt were evaluated after anesthetic induction, at surgery completion and in the first and second postoperative day and were compared for all groups by analysis of Variance for repeated measurements (p<0.05). Results: Data showed that Hb conc. (11±0.5), serum osmolarity (270±6), CAO2 (16.6±1.7), DaVO2 (4.8±1.8) decreased significantly in ICU for all groups expect for GP5. Serum creatinine for GP5 (0.85±0.1) is less than other groups
530 _aIssued also as CD
653 4 _aCardiopulmonary bypass
653 4 _aLung function and CPB
653 4 _aPriming solution
700 0 _aHosam Salh Eldin Elashmawi ,
_eSupervisor
700 0 _aMaha Anwar Ali ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c64251
_d64251