000 | 03536cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223031931.0 | ||
008 | 180219s2017 ua dh f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aM.Sc | ||
099 | _aCai01.11.28.M.Sc.2017.Na.R | ||
100 | 0 | _aNashwa Sayed Abdelhameed Abdelmegeed | |
245 | 1 | 0 |
_aRight ventricular function and pulmonary artery pressure in juvenile Systemic Lupus Erythematous with or without positive anticardiolipin Antibodies and their correlation to disease activity / _cNashwa Sayed Abdelhameed Abdelmegeed ; Supervised Samia Salah Eldin Mahmoud , Huda Marzouk Mohamed , Doaa Mohamed Abdelaziz |
246 | 1 | 5 | _aتحديد ارتفاع ضغط الشريان الرئوي و الخلل الوظيفي للبطين الايمن في حالات الذئبة الحمراء المصحوبة او غير المصحوبة بارتفاع الاجسام المضادة و علاقتها بنشاط المرض |
260 |
_aCairo : _bNashwa Sayed Abdelhameed Abdelmegeed , _c2017 |
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300 |
_a112 P. : _bcharts , facsimiles ; _c25cm |
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502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics | ||
520 | _aCardiovascular disease is a major cause of death in patients with systemic lupus erythematosus (SLE), especially during the late phase of the disease. Ventricular dysfunction is considered one of its common findings with overt morbidity and mortality. There is also some evidence about the association of antiphospholipid (aPL) antibodies with ventricular dysfunction in children with SLE and also there is a correlation between the activity of the disease and right ventricular dysfunction. This study aimed at evaluating the prevalence of echocardiographically documented systolic and diastolic right ventricular dysfunction in patients with SLE with or without anti-phospholipid antibodies, and to examine whether these antibodies are associated with right ventriclar dysfunction independently of valvular abnormalities and to evaluate the association of the disease activity with right ventricular function. Tissue Doppler echocardiography was performed on 30 patients with SLE whether they had antiphospholipid syndrome or not ,anticardiolipin antibodies was done to all patients and repeated after 6 weeks in positive cases and The disease activity using SLEDAI-2K score was done for all patients at the time of the study .Another 30 normal volunteer patients were taken as matched controls. 16 patients (53.3 %) had positive antiphospholipid antibodies, of whom 9 (30%) had positive aCL IgM, 7 (23.3%) had positive aCL IgG. 8 patients of those with positive APL antibodies had clinical evidence suggestive of antiphospholipid syndrome.The mean of the disease activity of all patients measured at the time of the study was 22 patients with venous manifestations of APS have higher SLEDAI score than patients with absent manifestations. No significant increase of pulmonary artery pressure in secondary antiphospholipid syndrome patients | ||
530 | _aIssued also as CD | ||
653 | 4 | _aRight ventricular function | |
653 | 4 | _aSLEDAI-2K | |
653 | 4 | _aSystemic Lupus Erythematosus | |
700 | 0 |
_aDoaa Mohamed Abdelaziz , _eSupervisor |
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700 | 0 |
_aHuda Marzouk Mohamed , _eSupervisor |
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700 | 0 |
_aSamia Salah Eldin Mahmoud , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aEnas _eCataloger |
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905 |
_aNazla _eRevisor |
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942 |
_2ddc _cTH |
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999 |
_c65086 _d65086 |