000 02856cam a2200325 a 4500
003 EG-GiCUC
008 180222s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.20.Ph.D.2017.Ha.M
100 0 _aHany Mohamed Ahmed
245 1 0 _aManagement of fourth ventricular ependymomas /
_cHany Mohamed Ahmed ; Supervised Amr mahmoud Safwat , Ahmed Salah Eldin Hassan , Mohamed A. Elbeltagy
246 1 5 _aعلاج الأورام البطانية العصبية بالبطين الرابع فى المخ
260 _aCairo :
_bHany Mohamed Ahmed ,
_c2017
300 _a123 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Neurosurgery
520 _aBackground: Ependymomas are rare neuroepithelial tumors which may arise anywhere along the ventricular system. Tumors arising in the 4th ventricle present unique challenges. Complete tumor resection favors prolonged survival, but may result in inadvertent injury of surrounding neural structures. Objective: to study clinical presentation, pathology, methods of investigations, operative techniques, complications of management of 4th ventricular ependymomas and eventually prognosis. Methods: This study was conducted upon forty patients with fourth ventricular ependymoma with variable ages at the time of diagnosis, admitted and managed at the Neurosurgery Department, at Kasr AL Ainy Hospital and Children{u2019}s Cancer Hospital-Egypt (CCHE-57357) between September 2015 and February 2017.Results: Total tumor excision was accomplished in 25 (62.5%) cases , near total resection in 5 (12.5%) cases, subtotal resection in 10(25%) cases. Pseudomenigocele occurred in 6 (15%) patients. Cerebellar mutism occurred in 4 (10%) patients. Bulbar manifestations was present in 5 (12%) cases.Tumor recurrence occurred in 4 (10%) patients during the follow-up period. Clinical outcome 3 weeks after surgery was excellent and good in 32 (80%) cases, fair and poor in 7 (17.5%) and there was one post operative mortality. Conclusion: Fourth ventricular ependymoma is a surgically treated disease. Extent of resection is considered the most important factor affecting prognosis of fourth ventricular ependymomas. Nevertheless, brain stem invasion and histopathological grade are also considered important factors affecting the outcome and prognosis
530 _aIssued also as CD
653 4 _aExtent of resection
653 4 _aFourth ventricular ependymoma
653 4 _aOutcome
700 0 _aAhmed Salah Eldin Hassan ,
_eSupervisor
700 0 _aAmr mahmoud Safwat ,
_eSupervisor
700 0 _aMohamed Ahmed Elbeltagy ,
_eSupervisor
905 _aEnas
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c65127
_d65127