000 03291cam a2200349 a 4500
003 EG-GiCUC
005 20250223031935.0
008 180225s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.31.Ph.D.2017.Fa.R
100 0 _aFatma Saber Elsayed Singer
245 1 4 _aThe role of diffusion weighted imaging with background signal suppression (DWIBS) in diagnosis of breast lesions :
_bComparison with contrast enhanced digital mammography (CEDM) /
_cFatma Saber Elsayed Singer ; Soha Talat Hamed , Noha Abdelshafy Elsaid , Marwa Anas Abdlrahman
246 1 5 _aتقييم دور الرنين المغناطيسي على الثدى مصحوبا بخاصية الانتشارومحو خلفية الجسم :
_bمقارنة مع الاشعة الرقميه للثدى بالصبغه فى امراض الثدى
260 _aCairo :
_bFatma Saber Elsayed Singer ,
_c2017
300 _a167 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
520 _aPurpose:The purpose of this study is to assess diagnostic performance and accuracy of diffusion weighted imaging with background signal suppression (DWIBS) compared with contrast enhanced mammography in diagnosis of breast lesions and correlate the findings with the histopathological results. Patients and methods :52 female patients were enrolled in the study their age ranged between 23-77 years old, mean age is about (47.83,+/-SD=11.55)years . All patients presented with BIRADS 3,4 and 5 lesions categorized by mammography and US . They were assessed by both contrast enhanced mammography and DWIBS MR.Each detected lesion was specified according to the BI-RADS classification, localization, and lesion size (maximum diameter) as well as the presence of additional sites of disease on both modalities.The imaging findings were correlated with the pathologic results. Results :The primary unit of analysis was the lesion ,54 lesions were detected in 52 cases.39/54 of the lesions were histopathologically proven as malignant and 15/54 were benign. The overall sensitivity of mammography, CEDM and DWIBS-MRI was 92.3%, 100% and 94.90% respectively .Their specificity was 60%,73.30% and 93.30% respectively. The area under the ROC curve was higher for DWIBS MRI (97.4%) than that was for CEDM (90.4 %) using BIRADS analysis The area under the ROC curve was higher for DWIBS MRI (97.4%) than that was for CEDM (90.4 %) using BIRADS analysis . So, DWIBS is betterin characterization of breast lesions.The cut off value of ADC for differentiation of benign from malignant lesions was suggested to be 1.15 {u00D7} 10{u2212}3 mm2with sensitivity of 94.90%, specificity of 80%The AUC was (AUC) = 0.913 with (95% Confidence Interval)
530 _aIssued also as CD
653 4 _aBIRADS
653 4 _aBreast
653 4 _aContrast mammography
700 0 _aMarwa Anas Abdlrahman ,
_eSupervisor
700 0 _aNoha Abdelshafy Elsaid ,
_eSupervisor
700 0 _aSoha Talat Hamed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c65176
_d65176