000			02954cam a2200349 a 4500
003			EG-GiCUC
005			20250223031938.0
008			180305s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.18.M.Sc.2017.Sa.D
100	0		_aSalma Mohamed Hosam Eldin Refaie
245	1	0	_aDetection of silent celiac disease in adult patients with type 1 diabetes mellitus by the use of anti tissue transglutaminase antibodies in Egyptian patients / _cSalma Mohamed Hosam Eldin Refaie ; Supervised Ahmed Abdlmoaty Alnaggar , Dina Sabry Abdlfattah , Hisham Mahmoud Abdallah
246	1	5	_aالكشف عن مرض السيلياك الصامت في مرضى النوع الاول من مرض السكر عن طريق استخدام الأجسام المضادة للأنسجة ناقلة الغلوتامين في المرضى المصريين البالغين
260			_aCairo : _bSalma Mohamed Hosam Eldin Refaie , _c2017
300			_a104 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
520			_aAIM: To detect the prevalence of silent celiac disease in adult patients with type 1 diabetes mellitus using serological immune-enzymatic tests, i.e., IgA antitissue transglutaminase antibodies (TgA- IgA), and IgG class in IgA deficient patients. Method: This is a prospective case-control study conducted from June 2016 to October 2016 on a cohort of 90 adult cases with T1DM compared to 48 adult healthy individuals aged between 20 and 40 years. All patients were subjected to routine labs, HbA1c, Anti TTG-IgA and selected Anti TTG-IgG in IgA negative cases. Results: The mean of age is 28.2 ± 6.26 years, 47.1 % males and 52.9% female, mean duration of diabetes range (among diabetic patients only) is 10.62 years ±7.13. Mean HbA1c among diabetics was 8.92 ± 1.5 , while among non diabetics was 5.26 ± 0.6. Anti TTG was (100 %) negative in controls while in diabetics, Anti TTG was (38.9%) negative and (61.1%) positive. Anti TTG IgG was selectively done for IgA negative (35 cases) and weak positive cases at cut-off value {u2264} 5 U/ml (22 cases) and only 3 cases (5.3%) were weak positive and 2 cases (3.5%) were strong positive for Anti TTG IgG while the remaining 91.2% were negative. Conclusion: Increased prevalence of IgA antitissue transglutaminase antibodies in adult patients with type 1 diabetes mellitus in comparison with control group
530			_aIssued also as CD
653		4	_aHbA1c
653		4	_aT1DM
653		4	_aTTG-IgA
700	0		_aAhmed Abdlmoaty Alnaggar , _eSupervisor
700	0		_aDina Sabry Abdlfattah , _eSupervisor
700	0		_aHisham Mahmoud Abdallah , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c65273 _d65273