000			03104cam a2200349 a 4500
003			EG-GiCUC
005			20250223031941.0
008			180311s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.31.M.Sc.2017.Em.A
100	0		_aEman Hosny Omar
245	1	4	_aThe additive role of dynamic post-contrast enhanced mri in women with increased risk of developing breast cancer / _cEman Hosny Omar ; supervised Rasha Mohamed Kamal Eldin , Eman Faker Kamal , Soha Mohamed Talima
246	1	5	_aالدور الاضافي للرنين المغناطيسي الديناميكي بالصبغة في السيدات الاكثر عرضه للإصابة بسرطان الثدي
260			_aCairo : _bEman Hosny Omar , _c2017
300			_a145 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
520			_aAim of the work: To assess the added value of DCE-MRI as a supplemental imaging modality to mammography in women with increased risk of developing breast cancer. Patients and methods: the study included 105 eligible female patients with increased risk of developing breast cancer(i.e. positive family history of breast cancer of first degree relative, personal history of breast cancer and heterogeneously dense mammary parenchyma ), full field digital mammography(FFDM) and DCE-MRI were performed,the findings were evaluated independently on both mammography and MRI scanning and final BI-RADS classifications was given ineach modality and compared to histopathology results as the golden standard. Results:In total, 105 women were enrolled in the study,the mean age of this study population is 45 years.Among the studied cases, regardless to a specific risk factor, 47/105 (44.7%) proved breast cancercases with histopathology (38 IDC,6 DCIS and 3 cases ILC), mammography detected 35/47 (74.5%) of these lesions and MRI scanning detected 45/47 (95.7%) cases,this giving an overall sensitivity of the MRI up to (95%)in this study in comparison to mammographic sensitivity (74% )while the specificity was(94.83%) and (87.93%)respectively,When comparing the mammography and DCE MRI findings within each risk factor group, the DCE MRI reported higher sensitivity than mammography (MRI study for patients with heterogeneously dense parenchyma reported (93.33%) sensitivity and (97.62%) specificity while the mammography reported significantly lower sensitivity of (66.67%) and specificity (92.86%), with significant P {u2013}value 0.001)
530			_aIssued also as CD
653		4	_aBIRADS classifications
653		4	_aDynamic contrast enhanced MRI breast
653		4	_aFull Field digital mammography(FFDM)
700	0		_aEman Faker Kamal , _eSupervisor
700	0		_aRasha Mohamed Kamal Eldin , _eSupervisor
700	0		_aSoha Mohamed Talima , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c65382 _d65382