000			02787cam a2200325 a 4500
003			EG-GiCUC
008			180311s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.18.M.Sc.2017.Sa.C
100	0		_aSafaa Mahfouz Ahmed
245	1	0	_aCorrelation between systemic lupus erythematosus disease activity and ocular signs in ophthalmologically asymptomatic patients / _cSafaa Mahfouz Ahmed ; Supervised Shawky Abdelhamid Fouad , Soheir Mohammed Esmat , Alshaimaa Rezk Lotfy Rezk
246	1	5	_aدراسة العلاقة بين نشاط مرض الذئبة الحمراء الجهازى و دلائلها على العين فى مرضى لا يعانون ضعف بصرى
260			_aCairo : _bSafaa Mahfouz Ahmed , _c2017
300			_a154 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine
520			_aSystemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease involving different organs and systems. Due to its heterogeneity, SLE is widely recognized as the prototype of systemic autoimmune disease. Ocular manifestations of lupus are fairly common, may be the presenting feature of the disease and can be sight-threatening. Almost any part of the eye and visual pathway can be affected by inflammatory or thrombotic processes Hydrochaine as an antimalarial drug is used for various autoimmune diseases as SLE and RA. The most concerning side effect is retinal toxicity and thus, it is vital for ophthalmologists to know the incidence, risk factors, drug toxicity and protocol screening of the patients who take this. Fifty two SLE cases ,middle aged and ophthalmologically asymptomatic, females and males patients, from SLE clinic of internal medicine department at Kasr Elainy hospital at Egypt. All patients were subjected to complete history taking ,detailed physical examination,clinical disease activity was assessed using SLEDAI Score. We concluded that lupus retinopathy is associated with disease activity ,could correlate and predict severe systemic association, make management earlier and more aggressive. The retinal signs often parallel the severity of systemic inflammation, and may indicate inadequate control of the systemic disease
530			_aIssued also as CD
653		4	_aLupus retinopathy
653		4	_aOCT and FFA in lupus retinopathy
653		4	_aSystemic lupus erythematosus (SLE)
700	0		_aAlshaimaa Rezk Lotfy Rezk , _eSupervisor
700	0		_aShawky Abdelhamid Fouad , _eSupervisor
700	0		_aSoheir Mohammed Esmat , _eSupervisor
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c65394 _d65394